Evidence map›Paper›PMID 28336465›Full record

ReviewTranslational research : the journal of laboratory and clinical medicine2017

Smoking and the risk of type 2 diabetes.

Judith Maddatu, Emily Anderson-Baucum, Carmella Evans-Molina

Abstract readReview
In one paragraph

Review in Translational research : the journal of laboratory and clinical medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 188 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
188citing papers in PubMed, 10 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

188 citing papers in PubMed, 10 syntheses or guidelines pooled it, 393 citations in OpenAlex.

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128 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Judith MaddatuDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Ind.
Emily Anderson-BaucumIndiana Biosciences Research Institute, Indianapolis, Ind.
Carmella Evans-MolinaDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Ind; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Ind; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Ind; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Ind; Roudebush VA Medical Center, Indianapolis, Ind. Electronic address: cevansmo@iu.edu.
Indiana University School of MedicineIndiana Biosciences Research Institute · US

Funding

Mechanisms of Beta Cell Function in Health and DiseaseR01DK093954 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI EVANS-MOLINA, CARMELLA · 2011 to 2019
$3.5M
Biomarkers Of Beta Cell Stress In Type 1 Diabetes (BetaMarker)UC4DK104166 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI EIZIRIK, DECIO LAKS, EVANS-MOLINA, CARMELLA · 2014 to 2014
$2.4M
The Role of Macrophage Deoxyhypusine Synthase in the Progression of Obesity-Associated Adipose Tissue InflammationF32DK104501 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI ANDERSON-BAUCUM, EMILY · 2015 to 2015
$52k
Regulation of Calcium Homeostasis in the Pancreatic Beta CellI01BX001733 · VA · RLR VA MEDICAL CENTER · PI Carmella Evans-Molina · 2013 to 2026
–
BLRD VA I01 BX001733NIDDK NIH HHS F32 DK104501NIDDK NIH HHS R01 DK093954NIDDK NIH HHS UC4 DK104166
6 · The paper itself

Abstract

Despite accumulating evidence demonstrating strong epidemiologic and mechanistic associations between cigarette smoking, hyperglycemia, and the development of type 2 diabetes, tobacco abuse has not been uniformly recognized as a modifiable risk factor in diabetes prevention or screening strategies. In this review, we highlight population-based studies that have linked cigarette smoking with an increased risk of type 2 diabetes and summarize clinical and preclinical studies offering insight into mechanisms through which cigarette smoking and nicotine exposure impact body composition, insulin sensitivity, and pancreatic β cell function. Key questions for future studies are identified and strategies for smoking cessation as a means to decrease diabetes risk are discussed.

Indexed as

Body CompositionBody WeightDiabetes, GestationalDiabetes Mellitus, Type 2FemaleGlucoseHomeostasisHumansInsulin ResistanceInsulin-Secreting CellsMalePregnancyRisk FactorsSmokingSmoking CessationGlucose

Identifiers

PMID28336465
PMCPMC5429867
OpenAlexW2594711611

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.