Evidence map›Paper›PMID 28336293›Full record

ArticleExperimental cell research2017

A compendium of proteins that interact with HIF-1α.

Gregg L Semenza

Abstract read
In one paragraph

Article in Experimental cell research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 108 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Lack of Hypoxia Inducible Factor-1α Influences on Macrophages Ability to Deal withJID innovations : skin science from molecules to population health · 2025
    Article
  8. Review
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  10. Article
  11. Review
  12. Review
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  14. Article
  15. Review
  16. Article
  17. Review
  18. BAP1 is a novel regulator of HIF-1α.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Gregg L SemenzaJohns Hopkins University School of Medicine, 733 N. Broadway, Baltimore, MD 21205 USA. Electronic address: gsemenza@jhmi.edu.
Johns Hopkins Medicine · US

Funding

Integrative Consequences of HypoxiaP01HL090554 · NHLBI · UNIVERSITY OF CHICAGO · PI PRABHAKAR, NANDURI R · 2008 to 2017
$21.4M
Aquaporin 1 and pulmonary hypertensionR01HL126514 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SHIMODA, LARISSA A. · 2015 to 2025
$4.5M
NHLBI NIH HHS HHSN268201000032CNHLBI NIH HHS P01 HL090554NHLBI NIH HHS R01 HL126514
6 · The paper itself

Abstract

Hypoxia-inducible factor 1 (HIF-1) is the founding member of a family of transcription factors that function as master regulators of oxygen homeostasis. HIF-1 is composed of an O

Indexed as

Aryl Hydrocarbon Receptor Nuclear TranslocatorCell HypoxiaHumansHypoxia-Inducible Factor 1, alpha SubunitNuclear ProteinsOxygenTranscription FactorsARNT protein, humanAryl Hydrocarbon Receptor Nuclear TranslocatorHypoxia-Inducible Factor 1, alpha SubunitNuclear ProteinsOxygenTranscription FactorsOxygen biologyTranscriptional regulation

Identifiers

PMID28336293
PMCPMC5541399
OpenAlexW2600632060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.