Evidence map›Paper›PMID 28336216›Full record

ArticleJournal of diabetes and its complications2017

Leptin is associated with cardiopulmonary fitness independent of body-mass index and insulin sensitivity in adolescents with type 1 diabetes: a brief report from the EMERALD study.

Petter Bjornstad, Melanie Cree-Green, Amy Baumgartner, Gregory Coe, Yesenia Garcia Reyes, Michal Schafer, Laura Pyle, Judith G Regensteiner, Jane E B Reusch, Kristen J Nadeau

Abstract read
In one paragraph

Article in Journal of diabetes and its complications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Petter BjornstadDepartment of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, CO, United States; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, CO. Electronic address: Petter.Bjornstad@childrenscolorado.org.
Melanie Cree-GreenDepartment of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, CO, United States; Center for Women's Health Research, Divisions of General Internal Medicine and Cardiology, University of Colorado School of Medicine, Aurora, CO, United States.
Amy BaumgartnerDepartment of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, CO, United States.
Gregory CoeDepartment of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, CO, United States.
Yesenia Garcia ReyesDepartment of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, CO, United States.
Michal SchaferDivision of Pediatric Cardiology, University of Colorado School of Medicine, Aurora, CO, United States.
Laura PyleDepartment of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, CO, United States.
Judith G RegensteinerCenter for Women's Health Research, Divisions of General Internal Medicine and Cardiology, University of Colorado School of Medicine, Aurora, CO, United States; Divisions of General Internal Medicine and Cardiology, University of Colorado School of Medicine, Aurora, CO, United States.
Jane E B ReuschCenter for Women's Health Research, Divisions of General Internal Medicine and Cardiology, University of Colorado School of Medicine, Aurora, CO, United States; Division of Endocrinology, Veterans Administration Hospital, University of Colorado School of Medicine, Aurora, CO, United States.
Kristen J NadeauDepartment of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, CO, United States; Center for Women's Health Research, Divisions of General Internal Medicine and Cardiology, University of Colorado School of Medicine, Aurora, CO, United States.
University of Colorado Denver · USChildren's Hospital Colorado · USUniversity of Colorado Hospital · US

Funding

Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
UCHSC: Building Interdisciplinary Research Careers in Women's HealthK12HD057022 · NICHD · UNIVERSITY OF COLORADO DENVER · PI REGENSTEINER, JUDITH G., SANTORO, NANETTE F. · 2007 to 2023
$8.5M
Training Program in Diabetes ResearchT32DK063687 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Andrea Steck · 2002 to 2026
$5.2M
Influence of peripheral insulin resistance and hepatic lipogenesis on liver fat in obese PCOS girlsK23DK107871 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI CREE, MELANIE G · 2015 to 2018
$743k
Insulin Control of Fat Regulation and Exercise in TeensK23RR020038 · NCRR · UNIVERSITY OF COLORADO DENVER · PI NADEAU, KRISTEN JANE · 2004 to 2008
$657k
Insulin Resistance In Adolescents With Diabetes: A New Frontier For CardiovasculaR56DK088971 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI NADEAU, KRISTEN JANE · 2010 to 2010
$215k
Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of SexI01CX001532 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI REUSCH, JANE E · 2017 to 2022
–
BLRD VA I01 BX002046CSRD VA I01 CX001532NCATS NIH HHS UL1 TR001082NCRR NIH HHS K23 RR020038NICHD NIH HHS K12 HD057022NIDDK NIH HHS K23 DK107871NIDDK NIH HHS R56 DK088971NIDDK NIH HHS T32 DK063687
6 · The paper itself

Abstract

Cardiopulmonary fitness is decreased in type 1 diabetes for reasons that are incompletely understood. In this study, leptin was associated with exercise capacity independent of insulin sensitivity (IS) and body mass index (BMI), suggesting that leptin may relate to cardiopulmonary fitness by mechanisms beyond IS and/or obesity.

Indexed as

AdiposityExercise ToleranceInsulin ResistanceAdolescentAdultBiomarkersBody Mass IndexCardiorespiratory FitnessChildColoradoDiabetes Mellitus, Type 1FemaleHumansLeptinMaleOverweightBiomarkersLeptinAdiposityCardiopulmonary fitnessInsulin sensitivityLeptinType 1 diabetes

Identifiers

PMID28336216
PMCPMC5426806
OpenAlexW2596315553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.