ReviewJournal of neuroimmunology2017
Varicella zoster virus vasculopathy: The expanding clinical spectrum and pathogenesis.
Review in Journal of neuroimmunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.
- Cerebral venous thrombosis in non-bacterial infections: a systematic review.BMC neurology · 2026Pooled it
- Fatal intracerebral hemorrhage in a pregnant woman following varicella zoster virus infection: a rare neurological complication.Forensic science, medicine, and pathology · 2026Article
- Increased risk of uveitis and optic neuritis after herpes zoster reactivation in COVID-19: a TriNetX database study.QJM : monthly journal of the Association of Physicians · 2026Article
- NSAIDs Use During Herpes Zoster Infection and Stroke Risk: A Nationwide Case-Crossover Study.Drug safety · 2026Article
- Impact of herpes zoster and post-zoster SGLT2 inhibitors initiation on cardiorenal outcomes in type 2 diabetes mellitus.BMC endocrine disorders · 2026Article
- Article
- Vertebral Artery Stump Syndrome Caused by Varicella-zoster Virus Vasculopathy in the Absence of a Skin Rash.Internal medicine (Tokyo, Japan) · 2026Article
- Beyond the Virological Benefits of the Herpes Zoster Vaccine in the Context of Primary Care.Vaccines · 2026Article
- Varicella Zoster Virus Vasculopathy Leading to a Recurrent Cerebral Infarction: Differential Treatment Responses Between Stenosis and Occlusion.Internal medicine (Tokyo, Japan) · 2025Article
- Fatal hemorrhagic leukoencephalitis following VZV reactivation in an immunocompetent host: a case report.Journal of neurology · 2025Article
- Markers of Giant Cell Arteritis in Patients Presenting With Ischemic Stroke: A Scoping Review.European journal of neurology · 2025Article
- Hemichorea as a primary manifestation of varicella-zoster virus neuroinfection in a child - a case report and review of literature.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Review
- A Diagnostic Approach to VZV Vasculopathy Using MR Vessel Wall Imaging.Internal medicine (Tokyo, Japan) · 2025Article
- Stroke, infections, and New Mechanisms: a Narrative Review.Current neurology and neuroscience reports · 2025Review
- Microvascular Density Analysis of Patients with Trigeminal Herpes Zoster-An Optical Coherence Tomography Angiography Study.Biomedicines · 2025Article
- [Vaccination and cardiovascular diseases].Herz · 2025Review
- Infectious diseases, cardio-cerebrovascular health and vaccines: pathways to prevention.Aging clinical and experimental research · 2025Review
- Varicella Pneumonia with Deep Venous Thrombosis and Pulmonary Embolism as Rare Presentations for Male: Case Report.Avicenna journal of medicine · 2025Article
- Understanding the Mode of Action of Several Active Ingredients from the Micro-Immunotherapy Medicine 2LZONAJournal of inflammation research · 2025Article
- The Diversity of Neurological Complications Associated with Herpes Zoster: A Retrospective Case Series of 26 Patients.Internal medicine (Tokyo, Japan) · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Varicella zoster virus (VZV) is a ubiquitous, human alphaherpesvirus that produces varicella on primary infection then becomes latent in ganglionic neurons along the entire neuraxis. In elderly and immunocompromised individuals, VZV reactivates and travels along nerve fibers peripherally resulting in zoster. However, VZV can also spread centrally and infect cerebral and extracranial arteries (VZV vasculopathy) to produce transient ischemic attacks, stroke, aneurysm, sinus thrombosis and giant cell arteritis, as well as granulomatous aortitis. The mechanisms of virus-induced pathological vascular remodeling are not fully elucidated; however, recent studies suggest that inflammation and dysregulation of programmed death ligand-1 play a significant role.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.