ArticleParasites & vectors2017
Canine tick-borne diseases in pet dogs from Romania.
Article in Parasites & vectors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- Two randomized, controlled studies to assess the efficacy and safety of lotilaner (Credelio™) in preventing Dermacentor reticulatus transmission of Babesia canis to dogs.Parasites & vectors · 2017Trial
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- Hepatozoon infections in domestic and wild Carnivora: etiology, prevalence, clinical disease, diagnosis and treatment, and redescription of Hepatozoon silvestris, H. martis, and H. ursi.Parasites & vectors · 2025Review
- Clinical Cases of Tick-Borne Diseases in Dogs During the Autumn-Winter Season in Poland.Pathogens (Basel, Switzerland) · 2024Article
- Lyme disease in companion animals: an updated state-of-art and current situation in Portugal.Veterinary research communications · 2024Review
- Molecular prevalence ofVeterinary world · 2024Article
- Molecular detection and characterization of Anaplasma marginale and Babesia canis vogeli infecting dogs in Luxor, Egypt.Scientific reports · 2024Article
- Vector-borne diseases imported to Poland between 2021 and 2023.Journal of veterinary research · 2024Article
- The first report on Hepatozoon canis in dogs and wolves in Poland: clinical and epidemiological features.Parasites & vectors · 2023Article
- Canine Babesiosis Caused by LargeAnimals : an open access journal from MDPI · 2023Review
- Molecular Survey and Genetic Characteristics of Vector-Borne Pathogens in Domestic Dogs from Four Regions of China.Animals : an open access journal from MDPI · 2023Article
- Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova.Pathogens (Basel, Switzerland) · 2022Article
- Prevalence ofVeterinary world · 2022Article
- Screening and phylogenetic characterization of tick-borne pathogens in a population of dogs and associated ticks in Egypt.Parasites & vectors · 2022Article
- Review
- Occurrence ofPathogens (Basel, Switzerland) · 2021Article
- Recreational behaviour, risk perceptions, and protective practices against ticks: a cross-sectional comparative study before and during the lockdown enforced by the COVID-19 pandemic in Romania.Parasites & vectors · 2021Article
- Comparison of conventional polymerase chain reaction and routine blood smear for the detection ofVeterinary world · 2019Article
- New records and host associations of the tick Ixodes apronophorus and the first detection of Ehrlichia sp. HF in Romania.Parasitology research · 2018Article
- Molecular survey of neglected bacterial pathogens reveals an abundant diversity of species and genotypes in ticks collected from animal hosts across Romania.Parasites & vectors · 2018Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTick-borne diseases are of substantial concern worldwide for animals as well as humans. Dogs have been a human companion for millennia, and their significant impact on human life renders disease in dogs to be of great concern. Tick-borne diseases in dogs represent a substantial diagnostic challenge for veterinarians in that clinical signs are often diffuse and overlapping. In addition, co-infections with two or more pathogens enhance this problem further. Molecular methods are useful to disentangle co-infections and to accurately describe prevalence and geographical distribution of tick-borne diseases. At this point, this information is lacking in many areas worldwide. Romania is one such area, where prevalence and distribution of several important pathogens need to be further investigated. To address this, we screened blood samples from 96 sick dogs with molecular methods for eight different pathogens including Babesia spp., Theileria spp., Hepatozoon spp., Anaplasma spp., Ehrlichia spp., "Candidatus Neoehrlichia mikurensis", Mycoplasma spp., and Borrelia spp.
resultsAs many as 45% (43/96) of the dogs in the study were infected with protozoan parasites. Babesia canis was the most frequent of these (28 infected dogs), whereas Hepatozoon canis was detected in 15% (14/96) and Babesia gibsoni was found in a single sample. Bacterial infection with Mycoplasma spp. occurred in 18% (17/96) of the sampled dogs. Obtained bacterial sequences revealed the occurrence of two species: Mycoplasma canis and "Candidatus Mycoplasma haematoparvum". In several cases co-infection with protozoan parasites and Mycoplasma sp. were detected. All dogs were negative for Anaplasma spp., Ehrlichia spp., "Ca. Neoehrlichia mikurensis", and for Borrelia spp.
conclusionsThe results from the present study reinforce the notion that Babesia canis is an important pathogen in the Romanian dog population. However, more surprisingly, another protozoan species, H. canis, seems to be infecting dogs to a larger extent than previously recognized in Romania. Well-known tick-borne bacterial disease agents such as Anaplasma spp. and Borrelia spp. were not detected. In contrast, less well-studied bacteria such as hemotropic Mycoplasma spp. were detected frequently. Moreover, co-infection might aggravate disease and complicate diagnosis and should be further studied in dogs.
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