Evidence map›Paper›PMID 28335818›Full record

ArticleBMC infectious diseases2017

Genotype distribution characteristics of multiple human papillomavirus in women from the Taihu River Basin, on the coast of eastern China.

Jing-Fen Lu, Guo-Rong Shen, Qiong Li, Xu Chen, Chun-Fang Ma, Tong-Hua Zhu

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Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing-Fen LuDepartment of Clinical laboratory, Wujiang First People's Hospital, Suzhou, People's Republic of China. petiteberyl@163.com.
Guo-Rong ShenDepartment of Clinical laboratory, Wujiang First People's Hospital, Suzhou, People's Republic of China.
Qiong LiDepartment of Clinical laboratory, Wujiang First People's Hospital, Suzhou, People's Republic of China.
Xu ChenDepartment of Clinical laboratory, Wujiang First People's Hospital, Suzhou, People's Republic of China.
Chun-Fang MaDepartment of Clinical laboratory, Wujiang First People's Hospital, Suzhou, People's Republic of China.
Tong-Hua ZhuDepartment of Clinical laboratory, Wujiang First People's Hospital, Suzhou, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is limited data on the genotype distribution of human papillomavirus (HPV) in the Taihu River Basin, home to 1.29 million people on the coast of eastern China. This study evaluated the prevalence and genotypes among different female age groups in this region.

methodsTwenty-six HPV strains (low-risk HPV 6, 11, 40, 42, 44, 61, 73 and high-risk HPV 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 55, 56, 58, 59, 66, 68, 82, and 83) were detected using Tellgenplex™ HPV technology in samples obtained from three clinical hospitals located in different regions of the Taihu Lake Basin.

resultsThe results showed that 1855 samples (20.97% of all samples) were found to be HPV-positive. Of these, 1375 samples (15.55% of all samples) were found to have a single HPV infection. Age-specific prevalence showed two peaks, one that corresponded to the group of 21-30 year-old women and the other peak that corresponded to the group of women over 51 years old. The three most prevalent genotypes were HPV52 (19.95%, 370/1855), HPV16 (13.48%, 150/1855), and HPV58 (11.32%, 210/1855). Mixed strains HPV58 + HPV33 and HPV58 + HPV52 were most commonly found in females infected with multiple HPV types.

conclusionsThis investigation reveals that HPV infection in the Taihu River Basin varied significantly among different age groups. The most prevalent genotypes are included in the nonavalent vaccine, V503, however this vaccine is not licensed for use in mainland China. The most frequently occurring genotypes should be considered in the development of next-generation HPV vaccines for optimal protection of public health.

Indexed as

GenotypeAdultAgedChinaDNA, ViralFemaleHumansMiddle AgedPapillomaviridaePapillomavirus InfectionsPapillomavirus VaccinesPrevalenceRiskRiversYoung AdultDNA, ViralPapillomavirus VaccinesCervical cancerDistributionGenotypesHuman papillomavirus

Identifiers

PMID28335818
PMCPMC5364703

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.