Evidence map›Paper›PMID 28335796›Full record

ArticleAlzheimer's research & therapy2017

Predicting dementia using socio-demographic characteristics and the Free and Cued Selective Reminding Test in the general population.

Thibault Mura, Marieta Baramova, Audrey Gabelle, Sylvaine Artero, Jean-François Dartigues, Hélène Amieva, Claudine Berr

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Alzheimer's research & therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Thibault MuraNeuropsychiatry: Epidemiological and Clinical Research, INSERM U1061, 34093, Montpellier, Cedex 5, France. t-mura@chu-montpellier.fr.ORCID http://orcid.org/0000-0001-6420-1336
Marieta BaramovaNeuropsychiatry: Epidemiological and Clinical Research, INSERM U1061, 34093, Montpellier, Cedex 5, France.
Audrey GabelleNeuropsychiatry: Epidemiological and Clinical Research, INSERM U1061, 34093, Montpellier, Cedex 5, France.
Sylvaine ArteroNeuropsychiatry: Epidemiological and Clinical Research, INSERM U1061, 34093, Montpellier, Cedex 5, France.
Jean-François DartiguesMemory Consultation, Centre Mémoire de Ressource et de Recherche, University Hospital, Bordeaux, France.
Hélène AmievaISPED, Centre INSERM U1219, Bordeaux Population Health Research Center, Bordeaux, France.
Claudine BerrNeuropsychiatry: Epidemiological and Clinical Research, INSERM U1061, 34093, Montpellier, Cedex 5, France.
Inserm · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur study aimed to determine whether the consideration of socio-demographic features improves the prediction of Alzheimer's dementia (AD) at 5 years when using the Free and Cued Selective Reminding Test (FCSRT) in the general older population.

methodsOur analyses focused on 2558 subjects from the prospective Three-City Study, a cohort of community-dwelling individuals aged 65 years and over, with FCSRT scores. Four "residual scores" and "risk scores" were built that included the FCSRT scores and socio-demographic variables. The predictive performance of crude, residual and risk scores was analyzed by comparing the areas under the ROC curve (AUC).

resultsIn total, 1750 subjects were seen 5 years after completing the FCSRT. AD was diagnosed in 116 of them. Compared with the crude free-recall score, the predictive performances of the residual score and of the risk score were not significantly improved (AUC: 0.83 vs 0.82 and 0.88 vs 0.89 respectively).

conclusionUsing socio-demographic features in addition to the FCSRT does not improve its predictive performance for dementia or AD.

Indexed as

Mental Status and Dementia TestsProportional Hazards ModelsAgedAged, 80 and overAge DistributionCausalityComorbidityCuesDementiaEducational StatusFemaleFranceHumansLongitudinal StudiesMaleMemory DisordersAlzheimer diseaseDementiaEarly clinical trialpreclinical Alzheimer diseasePredictionprodromal Alzheimer disease

Identifiers

PMID28335796
PMCPMC5364571
OpenAlexW2603859357

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.