ArticleRadiation oncology (London, England)2017
Tumor motion changes in stereotactic body radiotherapy for liver tumors: an evaluation based on four-dimensional cone-beam computed tomography and fiducial markers.
Article in Radiation oncology (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 62 citations in OpenAlex.
- Dosimetric comparison of gamma knife and linear accelerator (VMAT and IMRT) plans of SBRT of Lung tumours.Scientific reports · 2024Article
- A review on 4D cone-beam CT (4D-CBCT) in radiation therapy: Technical advances and clinical applications.Medical physics · 2024Review
- Towards quantitative in vivo dosimetry using x-ray acoustic computed tomography.Medical physics · 2023Article
- Article
- Development of a novel airbag system of abdominal compression for reducing respiratory motion: preliminary results in healthy volunteers.Journal of radiation research · 2022Article
- The first internal electromagnetic motion monitoring implementation for stereotactic liver radiotherapy in China: procedures and preliminary results.Journal of cancer research and clinical oncology · 2022Article
- Real-time liver tumor localization via a single x-ray projection using deep graph neural network-assisted biomechanical modeling.Physics in medicine and biology · 2022Article
- Article
- Quantifying 6D tumor motion and calculating PTV margins during liver stereotactic radiotherapy with fiducial tracking.Frontiers in oncology · 2022Article
- Automatic liver tumor localization using deep learning-based liver boundary motion estimation and biomechanical modeling (DL-Bio).Medical physics · 2021Article
- First-in-human imaging using a MR-compatible e4D ultrasound probe for motion management of radiotherapy.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2021Article
- Impact of four-dimensional cone-beam computed tomography on target localization for gastric mucosa-associated lymphoid tissue lymphoma radiotherapy: reducing planning target volume.Radiation oncology (London, England) · 2021Article
- Prospective evaluation of fiducial marker placement quality and toxicity in liver CyberKnife stereotactic body radiotherapy.Radiation oncology journal · 2020Article
- Definition of internal target volumes based on planar X-ray fluoroscopic images for lung and hepatic stereotactic body radiation therapy. Comparison to inhale/exhale CT technique.Journal of applied clinical medical physics · 2020Article
- Investigation of tumor and vessel motion correlation in the liver.Journal of applied clinical medical physics · 2020Article
- respiTrack: Patient-specific real-time respiratory tumor motion prediction using magnetic tracking.International journal of computer assisted radiology and surgery · 2020Article
- Estimation of effective imaging dose and excess absolute risk of secondary cancer incidence for four-dimensional cone-beam computed tomography acquisition.Journal of applied clinical medical physics · 2019Article
- Estimating intrafraction tumor motion during fiducial-based liver stereotactic radiotherapy via an iterative closest point (ICP) algorithm.Radiation oncology (London, England) · 2019Article
- Assessment of setup uncertainty in hypofractionated liver radiation therapy with a breath-hold technique using automatic image registration-based image guidance.Radiation oncology (London, England) · 2019Article
- Role of Radiotherapy in the Treatment of Hepatocellular Carcinoma.Journal of clinical and translational hepatology · 2019Review
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11 authors at 2 institutions in 1 country.
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Abstract
backgroundFor stereotactic body radiation therapy (SBRT) of liver tumors, tumor motion induced by respiration must be taken into account in planning and treatment. We evaluated whether liver tumor motion at the planning simulation represents liver tumor motion during SBRT, and estimated inter- and intrafractional tumor motion changes in patients undergoing liver SBRT.
methodsTen patients underwent four-dimensional cone-beam computed tomography (4D-CBCT) image-guided liver SBRT with abdominal compression (AC) and fiducial markers. 4D-CBCT was performed to evaluate liver tumor motion at the planning simulation, pre-, and post-SBRT. The translational distances at the center position of the fiducial markers from all 10 phases on the 4D-CBCT images were measured as the extent of the liver tumor motion in the left-right (LR), anterior-posterior (AP), and superior-inferior (SI) directions. Pearson correlation coefficients were calculated to evaluate the correlation between liver tumor motion of the planning simulation and the mean liver tumor motion of the pre-SBRT. Inter- and intrafractional liver tumor motion changes were measured based on the 4D-CBCT of planning simulation, pre-, and post-SBRT. Significant inter- and intrafractional changes in liver tumor motion were defined as a change of >3 mm.
resultsThe mean (± SD) liver tumor motion of the planning simulation 4D-CBCT was 1.7 ± 0.8 mm, 2.4 ± 2.2 mm, and 5.3 ± 3.3 mm, in the LR, AP, and SI directions, respectively. Those of the pre-SBRT 4D-CBCT were 1.2 ± 0.7 mm, 2.3 ± 2.3 mm, and 4.5 ± 3.8 mm, in the LR, AP, and SI directions, respectively. There was a strong significant correlation between liver tumor motion of the planning simulation and pre-SBRT in the LR (R = 0.7, P < 0.01), AP (R = 0.9, P < 0.01), and SI (R = 0.9, P < 0.01) directions. Significant inter- and intrafractional liver tumor motion changes occurred in 10 and 2% of treatment fractions, respectively.
conclusionsLiver tumor motion at the planning simulation represents liver tumor motion during SBRT. Inter- and intrafractional liver tumor motion changes were small in patients with AC.
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