Evidence map›Paper›PMID 28335560›Full record

ArticleNutrients2017

Serum Amyloid A Production Is Triggered by Sleep Deprivation in Mice and Humans: Is That the Link between Sleep Loss and Associated Comorbidities?

Edson M de Oliveira, Bruna Visniauskas, Sergio Tufik, Monica L Andersen, Jair R Chagas, Ana Campa

Abstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Frontiers in pharmacology · 2026
    Article
  2. Human serum proteomics reveals a molecular signature after one night of sleep deprivation.Sleep advances : a journal of the Sleep Research Society · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edson M de OliveiraDepartamento de Análises Clínicas e Toxicológicas, Universidade de São Paulo, Av. Prof. Lineu Prestes, 580, São Paulo SP 05509-000, Brazil. edson.fbq@gmail.com.
Bruna VisniauskasDepartamento de Psicobiologia, Universidade Federal de São Paulo, Rua Napoleão de Barros, 925, São Paulo SP 04024-002, Brazil. brunavisniauskas@gmail.com.
Sergio TufikDepartamento de Psicobiologia, Universidade Federal de São Paulo, Rua Napoleão de Barros, 925, São Paulo SP 04024-002, Brazil. sergio.tufik@unifesp.br.
Monica L AndersenDepartamento de Psicobiologia, Universidade Federal de São Paulo, Rua Napoleão de Barros, 925, São Paulo SP 04024-002, Brazil. ml.andersen12@gmail.com.
Jair R ChagasDepartamento de Psicobiologia, Universidade Federal de São Paulo, Rua Napoleão de Barros, 925, São Paulo SP 04024-002, Brazil. jchagas1@gmail.com.
Ana CampaDepartamento de Análises Clínicas e Toxicológicas, Universidade de São Paulo, Av. Prof. Lineu Prestes, 580, São Paulo SP 05509-000, Brazil. anacampa@usp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum amyloid A (SAA) was recently associated with metabolic endotoxemia, obesity and insulin resistance. Concurrently, insufficient sleep adversely affects metabolic health and is an independent predisposing factor for obesity and insulin resistance. In this study we investigated whether sleep loss modulates SAA production. The serum SAA concentration increased in C57BL/6 mice subjected to sleep restriction (SR) for 15 days or to paradoxical sleep deprivation (PSD) for 72 h. Sleep restriction also induced the upregulation of

Indexed as

AdultAnimalsBiomarkersBody WeightComorbidityDisease Models, AnimalGene Expression RegulationHumansLiverMaleMiceMice, Inbred C57BLObesityRNA, MessengerSerum Amyloid A ProteinSleep DeprivationBiomarkersRNA, MessengerSerum Amyloid A ProteinobesitySAAsleep curtailmentsleep losstype 2 diabetes

Identifiers

PMID28335560
PMCPMC5372974

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.