Evidence map›Paper›PMID 28335551›Full record

ReviewInternational journal of molecular sciences2017

Molecular Basis for Modulation of Metabotropic Glutamate Receptors and Their Drug Actions by Extracellular Ca

Juan Zou, Jason Y Jiang, Jenny J Yang

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Illuminating the allosteric modulation of the calcium-sensing receptor.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Juan ZouDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA. jzou2@student.gsu.edu.
Jason Y JiangDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA. yusheng0104@gmail.com.
Jenny J YangDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA. jenny@gsu.edu.
Georgia State University · US

Funding

Designing Magnetic Resonance Protein-based Contrast Agents with High RelaxivityR01EB007268 · NIBIB · GEORGIA STATE UNIVERSITY · PI YANG, JENNY J. · 2007 to 2015
$3.1M
GAP JUNCTIONS AND IONIC CURRENTS IN DEVELOPING HEARTR01HL042220 · NHLBI · UPSTATE MEDICAL UNIVERSITY · PI VEENSTRA, RICHARD DAVID, YANG, JENNY J. · 1988 to 2013
$3.1M
Noninvasive Contrast Enhanced Early Detection of Melanoma Liver MetastasisR42CA183376 · NCI · INLIGHTA BIOSCIENCES, LLC · PI YANG, JENNY J. · 2017 to 2019
$2.0M
Rational Design and Analysis of Calcium Binding ProteinR01GM062999 · NIGMS · GEORGIA STATE UNIVERSITY · PI YANG, JENNY J · 2001 to 2005
$991k
Molecular Imaging of Early Stage of Liver Fibrosis by Novel Protein AgentsR41AA025863 · NIAAA · INLIGHTA BIOSCIENCES, LLC · PI YANG, JENNY J. · 2016 to 2016
$239k
NCI NIH HHS R42 CA183376NIAAA NIH HHS R41 AA025863NIBIB NIH HHS R01 EB007268NIGMS NIH HHS R01 GM062999
6 · The paper itself

Abstract

Metabotropic glutamate receptors (mGluRs) associated with the slow phase of the glutamatergic signaling pathway in neurons of the central nervous system have gained importance as drug targets for chronic neurodegenerative diseases. While extracellular Ca

Indexed as

Allosteric RegulationAnimalsCalciumCalcium SignalingHumansNeuronsReceptors, Metabotropic GlutamateCalciumReceptors, Metabotropic Glutamateextracellular Ca2+family C of G-protein coupled receptor (cGPCR)metabotropic glutamate receptor (mGluR)regulation

Identifiers

PMID28335551
PMCPMC5372683
OpenAlexW2600856095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.