Evidence map›Paper›PMID 28335516›Full record

ArticleMarine drugs2017

Marine Diterpenes: Molecular Modeling of Thrombin Inhibitors with Potential Biotechnological Application as an Antithrombotic.

Rebeca Cristina Costa Pereira, André Luiz Lourenço, Luciana Terra, Paula Alvarez Abreu, Valéria Laneuville Teixeira, Helena Carla Castro

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Marine drugs · 2025
    Article
  2. Review
  3. Volatile Organic Compound Profiles ofMolecules (Basel, Switzerland) · 2022
    Article
  4. Seasonal Variability of Volatilome fromMolecules (Basel, Switzerland) · 2022
    Article
  5. Marine Natural Products and Coronary Artery Disease.Frontiers in cardiovascular medicine · 2021
    Review
  6. Marine Antithrombotics.Marine drugs · 2020
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rebeca Cristina Costa PereiraPrograma de Pós-Graduação em Ciências e Biotecnologia (PPBI), Instituto de Biologia, Universidade Federal Fluminense, Niterói 24210-130, RJ, Brazil. rebecaccpereira@gmail.com.
André Luiz LourençoLaboratório de Trombose e Câncer, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21944-970, RJ, Brazil. andrebiouff@gmail.com.
Luciana TerraPrograma de Pós-Graduação em Ciências e Biotecnologia (PPBI), Instituto de Biologia, Universidade Federal Fluminense, Niterói 24210-130, RJ, Brazil. luterra.santos@gmail.com.
Paula Alvarez AbreuLaboratório de Modelagem Molecular e Pesquisa em Ciências Farmacêuticas-LAMCIFAR, NUPEM, Universidade Federal do Rio de Janeiro, Campus Macaé, Rio de Janeiro27965-045, RJ, Brazil. abreu_pa@yahoo.com.br.
Valéria Laneuville TeixeiraPrograma de Pós-Graduação em Ciências e Biotecnologia (PPBI), Instituto de Biologia, Universidade Federal Fluminense, Niterói 24210-130, RJ, Brazil. valerialaneuville@gmail.com.
Helena Carla CastroPrograma de Pós-Graduação em Ciências e Biotecnologia (PPBI), Instituto de Biologia, Universidade Federal Fluminense, Niterói 24210-130, RJ, Brazil. hcastrorangel@yahoo.com.br.
Universidade Federal Fluminense · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombosis related diseases are among the main causes of death and incapacity in the world. Despite the existence of antithrombotic agents available for therapy, they still present adverse effects like hemorrhagic risks which justify the search for new options. Recently, pachydictyol A, isopachydictyol A, and dichotomanol, three diterpenes isolated from Brazilian marine brown alga

Indexed as

AnticoagulantsAquatic OrganismsBlood CoagulationBrazilDiterpenesFibrinolytic AgentsModels, MolecularMolecular Docking SimulationPhaeophyceaeStructure-Activity RelationshipThrombinThrombosisAnticoagulantsDiterpenesFibrinolytic AgentsThrombinanticoagulantantithromboticDictyota menstrualisditerpenesmarine productsmolecular docking

Identifiers

PMID28335516
PMCPMC5367036
OpenAlexW2597922229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.