Evidence map›Paper›PMID 28335495›Full record

ArticleInternational journal of molecular sciences2017

Brain-Derived Neurotrophic Factor Loaded PS80 PBCA Nanocarrier for In Vitro Neural Differentiation of Mouse Induced Pluripotent Stem Cells.

Chiu-Yen Chung, Martin Hsiu-Chu Lin, I-Neng Lee, Tsong-Hai Lee, Ming-Hsueh Lee, Jen-Tsung Yang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Stem cells technology: a powerful tool behind new brain treatments.Drug delivery and translational research · 2018
    Review
  8. [Efficacy of brain-targeted rapamycin for treatment of epilepsy in rats].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2018
    Article
  9. Impact of nanoparticles on neuron biology: current research trends.International journal of nanomedicine · 2018
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chiu-Yen ChungDepartment of Neurosurgery, Chang Gung Memorial Hospital, Chia-Yi 61363, Taiwan. yen5103106@gmail.com.
Martin Hsiu-Chu LinDepartment of Neurosurgery, Chang Gung Memorial Hospital, Chia-Yi 61363, Taiwan. martin.lin@uclmail.net.
I-Neng LeeDepartment of Medical Research, Chang Gung Memorial Hospital, Chia-Yi 61363, Taiwan. geneasylum@yahoo.com.tw.
Tsong-Hai LeeCollege of Medicine, Chang Gung University, Tao-Yuan 33302, Taiwan. thlee@adm.cgmh.org.tw.
Ming-Hsueh LeeDepartment of Neurosurgery, Chang Gung Memorial Hospital, Chia-Yi 61363, Taiwan. ming2072@cgmh.org.tw.
Jen-Tsung YangDepartment of Neurosurgery, Chang Gung Memorial Hospital, Chia-Yi 61363, Taiwan. jents716@ms32.hinet.net.
Chiayi Chang Gung Memorial Hospital · TWChang Gung Memorial Hospital · TWChang Gung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain derived neurotrophic factor (BDNF) can induce neural differentiation in stem cells and has the potential for repair of the nervous system. In this study, a polysorbate 80-coated polybutylcyanoacrylate nanocarrier (PS80 PBCA NC) was constructed to deliver plasmid DNAs (

Indexed as

Cell DifferentiationAnimalsBrain-Derived Neurotrophic FactorCell HypoxiaCell LineEnbucrilateGenetic VectorsHypoxia-Inducible Factor 1, alpha SubunitInduced Pluripotent Stem CellsMiceNanoparticlesNeuronsPhosphatidylinositol 3-KinasesPolysorbatesProto-Oncogene Proteins c-aktResponse ElementsBrain-Derived Neurotrophic FactorEnbucrilateHypoxia-Inducible Factor 1, alpha SubunitPhosphatidylinositol 3-KinasesPolysorbatesProto-Oncogene Proteins c-aktRNARNA, recombinantbrain-derived neurotrophic factorhypoxia-responsive elementinduced pluripotent stem cellpolybutylcyanoacrylate nanocarrier

Identifiers

PMID28335495
PMCPMC5372675
OpenAlexW2603505858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.