Evidence map›Paper›PMID 28335472›Full record

ArticleDiagnostics (Basel, Switzerland)2017

Detecting Breast Cancer with a Dual-Modality Device.

Kamila Padia, Tania S Douglas, Lydia L Cairncross, Roland V Baasch, Christopher L Vaughan

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kamila PadiaDepartment of Radiology, 2 Military Hospital, Hospital Street, Wynberg 7800, South Africa. kamilanaidoo@iafrica.com.
Tania S DouglasMedical Imaging Research Unit, University of Cape Town, Observatory 7925, South Africa. tania.douglas@uct.ac.za.
Lydia L CairncrossDepartment of Surgery, Groote Schuur Hospital and University of Cape Town, Observatory 7925, South Africa. roland@caperay.com.
Roland V BaaschCapeRay Medical (Pty) Ltd, 51 Bell Crescent, Westlake Business Park 7945, South Africa. lydia.cairncross@uct.ac.za.
Christopher L VaughanMedical Imaging Research Unit, University of Cape Town, Observatory 7925, South Africa. kit@caperay.com.

Funding

Low dose digital X-rays for mammographic screeningR21CA101705 · NCI · UNIVERSITY OF CAPE TOWN · PI VAUGHAN, CHRISTOPHER L · 2005 to 2006
$235k
NCI NIH HHS R21 CA101705
6 · The paper itself

Abstract

Although mammography has been the gold standard for the early detection of breast cancer, if a woman has dense breast tissue, a false negative diagnosis may occur. Breast ultrasound, whether hand-held or automated, is a useful adjunct to mammography but adds extra time and cost. The primary aim was to demonstrate that our second-generation Aceso system, which combines full-field digital mammography (FFDM) and automated breast ultrasound (ABUS) in a single platform, is able to produce improved quality images that provide clinically meaningful results. Aceso was first tested using two industry standards: a Contrast Detail Mammography (CDMAM) phantom to assess the FFDM images, and the CIRS 054GS phantom to evaluate the ABUS images. In addition, 25 women participated in a clinical trial: 14 were healthy volunteers, while 11 were patients referred by the breast clinic at Groote Schuur Hospital. The CDMAM phantom results showed the FFDM results were better than the European Reference (EUREF) standard of "acceptable" and were approaching "achievable". The ABUS results showed a lateral and axial spatial resolution of 0.5 mm and an adequate depth penetration of 80 mm. Our second-generation Aceso system, with its improved quality of clinical FFDM and ABUS images, has demonstrated its potential for the early detection of breast cancer in a busy clinic.

Indexed as

automated breast ultrasound (ABUS)breast cancerdense breastsdual-modality imagingfull-field digital mammography (FFDM)

Identifiers

PMID28335472
PMCPMC5373026

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.