Evidence map›Paper›PMID 28334696›Full record

ArticleJournal of the Royal Society, Interface2016

Effects of hypergravity on the angiogenic potential of endothelial cells.

Raquel Costa-Almeida, Daniel T O Carvalho, Miguel J S Ferreira, Guilherme Aresta, Manuela E Gomes, Jack J W A van Loon, Kim Van der Heiden, Pedro L Granja

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Raquel Costa-Almeida3B's Research Group-Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Guimarães, Portugal.ORCID 0000-0001-7188-645X
Daniel T O Carvalhoi3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Miguel J S Ferreirai3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Guilherme ArestaICBAS-Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.
Manuela E Gomes3B's Research Group-Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Guimarães, Portugal.
Jack J W A van LoonDepartment of Oral and Maxillofacial Surgery/Oral Pathology, VU-University Medical Center, Amsterdam, The Netherlands.
Kim Van der HeidenDepartment of Biomedical Engineering, ErasmusMC, Rotterdam, The Netherlands.
Pedro L Granjai3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal pgranja@i3s.up.pt.ORCID 0000-0003-2761-4929
Universidade do Porto · PTUniversity of Minho · PTErasmus MC · NLEuropean Space Research and Technology Centre · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenesis, the formation of blood vessels from pre-existing ones, is a key event in pathology, including cancer progression, but also in homeostasis and regeneration. As the phenotype of endothelial cells (ECs) is continuously regulated by local biomechanical forces, studying endothelial behaviour in altered gravity might contribute to new insights towards angiogenesis modulation. This study aimed at characterizing EC behaviour after hypergravity exposure (more than 1

Indexed as

HypergravityNeovascularization, PhysiologicActinsHumansHuman Umbilical Vein Endothelial CellsTubulinActinsTubulinaltered gravitycapillary-like structurescytoskeletonhypergravity pre-stimulationthree-dimensional matrigel

Identifiers

PMID28334696
PMCPMC5134019
OpenAlexW2549638856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.