Evidence map›Paper›PMID 28334695›Full record

ArticleJournal of the Royal Society, Interface2016

How the embryonic chick brain twists.

Zi Chen, Qiaohang Guo, Eric Dai, Nickolas Forsch, Larry A Taber

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Cilia-driven epithelial folding and unfolding in an early diverging animal.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Zi ChenDepartment of Biomedical Engineering, Washington University, St Louis, MO 63130, USA zi.chen@dartmouth.edu.ORCID 0000-0001-5927-0249
Qiaohang GuoSchool of Materials Science and Engineering, Fujian University of Technology, Fuzhou 350108, People's Republic of China.
Eric DaiDepartment of Biomedical Engineering, Washington University, St Louis, MO 63130, USA.
Nickolas ForschDepartment of Biomedical Engineering, Washington University, St Louis, MO 63130, USA.
Larry A TaberDepartment of Biomedical Engineering, Washington University, St Louis, MO 63130, USA.
Washington University in St. Louis · USDartmouth College · USFujian University of Technology · CN

Funding

MECHANICS OF EARLY BRAIN AND EYE DEVELOPMENTR01NS070918 · NINDS · WASHINGTON UNIVERSITY · PI TABER, LARRY A · 2010 to 2014
$1.6M
Computational Modeling of Developmental ProcessesR01GM075200 · NIGMS · WASHINGTON UNIVERSITY · PI TABER, LARRY A · 2006 to 2009
$1.2M
NIGMS NIH HHS R01 GM075200NINDS NIH HHS R01 NS070918
6 · The paper itself

Abstract

During early development, the tubular embryonic chick brain undergoes a combination of progressive ventral bending and rightward torsion, one of the earliest organ-level left-right asymmetry events in development. Existing evidence suggests that bending is caused by differential growth, but the mechanism for the predominantly rightward torsion of the embryonic brain tube remains poorly understood. Here, we show through a combination of

Indexed as

ChickensModels, BiologicalAnimalsBrainChick EmbryoOrganogenesisVitelline Membraneaxial rotationbiomechanicsembryonic developmentleft–right asymmetrytorsion

Identifiers

PMID28334695
PMCPMC5134006
OpenAlexW2556748248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.