ReviewCancer2017
Risk-reducing salpingectomy: Let us be opportunistic.
Review in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03171467 (Salpingectomy in Women Undergoing Elective Laparoscopic Cholecystectomy), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Salpingectomy in Women Undergoing Elective Laparoscopic Cholecystectomy (SaLCHE): A Feasibility Study
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Hysterectomy with opportunistic salpingectomy versus hysterectomy alone.The Cochrane database of systematic reviews · 2019Pooled it
- Uptake and timing of risk-reducing gynecologic surgery among individuals with Lynch syndrome identified via population screening.Familial cancer · 2026Article
- Mechanistic insights into c-Met rs368750834 mutation and a bifunctional CAR-T strategy for serous ovarian carcinoma.Journal of ovarian research · 2025Article
- Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) in Risk-Reducing Gynecologic Cancer Surgery: A New Frontier in Hereditary Cancer Prevention.Journal of clinical medicine · 2025Review
- Global epidemiology of epithelial ovarian cancer.Nature reviews. Clinical oncology · 2024Review
- Unveiling the Promise: A Comprehensive Review of Salpingectomy as a Vanguard for Ovarian Cancer Prevention.Cureus · 2024Review
- Recovery of the Decreased Phagocytic Function of Peripheral Monocytes and Neutrophil Granulocytes following Cytoreductive Surgery in Advanced Stage Epithelial Ovarian Cancer.Medicina (Kaunas, Lithuania) · 2023Article
- Long-Term Follow Up of Sexual Function and Steroid Levels in Women after Perimenopausal Hysterectomy with or without Concomitant Oophorectomy.Journal of clinical medicine · 2023Article
- A Study to Evaluate the Effect of Opportunistic Salpingectomy on Ovarian Reserve and Function.Journal of obstetrics and gynaecology of India · 2023Article
- Endometriosis and the Fallopian Tubes: Theories of Origin and Clinical Implications.Journal of clinical medicine · 2020Review
- Before it catches the eye….Annals of translational medicine · 2019Article
- Incidence of intraepithelial fallopian tube neoplasias in mexican women over 40 years of age that underwent elective hysterectomy.Journal of ovarian research · 2019Observational
- Ovarian Cancer Previvors: How to manage these patients?Clinics (Sao Paulo, Brazil) · 2019Article
- Tubal Origin of "Ovarian" Low-Grade Serous Carcinoma: A Gene Expression Profile Study.Journal of oncology · 2019Article
- Bilateral salpingectomy to reduce the risk of ovarian/fallopian/peritoneal cancer in women at average risk: a position statement of the Korean Society of Obstetrics and Gynecology (KSOG).Obstetrics & gynecology science · 2018Review
- Identification of candidate genes associated with tubal origin of high-grade serous ovarian cancer.Oncology letters · 2018Article
- Recommendations and Choices for BRCA Mutation Carriers at Risk for Ovarian Cancer: A Complicated Decision.Cancers · 2018Review
- Trends of Opportunistic Salpingectomy.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Because there is no screening test for ovarian cancer, effective prevention strategies may be the best way to reduce the mortality of this most lethal gynecologic malignancy. Increasing evidence supports the hypothesis that the fallopian tube is the site of origin for the vast majority of high-grade serous carcinomas. Our growing understanding of the pathogenesis of this disease offers a rare opportunity to explore new preventive measures, such as bilateral salpingectomy, which may provide great benefit without compromising ovarian function. If the tubal paradigm is accurate, then the impact of bilateral salpingectomy could extend to BRCA1 and BRCA2 mutation carriers, high-risk noncarriers, and average-risk women. The authors present a review of the literature on the role of risk-reducing salpingectomy in all women and in high-risk groups, with a focus on morbidity, ovarian function, potential clinical applicability, and epidemiological considerations. Cancer 2017;123:1714-1720. © 2017 American Cancer Society.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.