Evidence map›Paper›PMID 28334358›Full record

ArticleJournal of biomechanical engineering2017

Ranges of Cervical Intervertebral Disc Deformation During an In Vivo Dynamic Flexion-Extension of the Neck.

Yan Yu, Haiqing Mao, Jing-Sheng Li, Tsung-Yuan Tsai, Liming Cheng, Kirkham B Wood, Guoan Li, Thomas D Cha

Abstract read
In one paragraph

Article in Journal of biomechanical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yan YuDepartment of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai 2000065, China;Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.
Haiqing MaoDepartment of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu, China.
Jing-Sheng LiCollege of Health and Rehabilitation Sciences, Sargent College, Boston University, Boston, MA 02215.
Tsung-Yuan TsaiSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China.
Liming ChengDepartment of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China.
Kirkham B WoodDepartment of Orthopaedic Surgery, Stanford University Medical Center, Redwood City, CA 94063.
Guoan LiDepartment of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, GRJ 1215, Boston, MA 02114 e-mail: guoanli12@gmail.com.
Thomas D ChaDepartment of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.

Funding

In-vivo Lumbar Disc DeformationR21AR057989 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI LI, GUOAN · 2010 to 2011
$432k
NIAMS NIH HHS R21 AR057989
6 · The paper itself

Abstract

While abnormal loading is widely believed to cause cervical spine disc diseases, in vivo cervical disc deformation during dynamic neck motion has not been well delineated. This study investigated the range of cervical disc deformation during an in vivo functional flexion-extension of the neck. Ten asymptomatic human subjects were tested using a combined dual fluoroscopic imaging system (DFIS) and magnetic resonance imaging (MRI)-based three-dimensional (3D) modeling technique. Overall disc deformation was determined using the changes of the space geometry between upper and lower endplates of each intervertebral segment (C3/4, C4/5, C5/6, and C6/7). Five points (anterior, center, posterior, left, and right) of each disc were analyzed to examine the disc deformation distributions. The data indicated that between the functional maximum flexion and extension of the neck, the anterior points of the discs experienced large changes of distraction/compression deformation and shear deformation. The higher level discs experienced higher ranges of disc deformation. No significant difference was found in deformation ranges at posterior points of all the discs. The data indicated that the range of disc deformation is disc level dependent and the anterior region experienced larger changes of deformation than the center and posterior regions, except for the C6/7 disc. The data obtained from this study could serve as baseline knowledge for the understanding of the cervical spine disc biomechanics and for investigation of the biomechanical etiology of disc diseases. These data could also provide insights for development of motion preservation surgeries for cervical spine.

Indexed as

Mechanical PhenomenaAdultBiomechanical PhenomenaCervical VertebraeFemaleHumansIntervertebral DiscIntervertebral Disc DegenerationIntervertebral Disc DisplacementMaleModels, AnatomicNeckRange of Motion, ArticularTomography, X-Ray Computed

Identifiers

PMID28334358
PMCPMC5444210

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.