Evidence map›Paper›PMID 28334214›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2018

tDCS Modulates Visual Gamma Oscillations and Basal Alpha Activity in Occipital Cortices: Evidence from MEG.

Tony W Wilson, Timothy J McDermott, Mackenzie S Mills, Nathan M Coolidge, Elizabeth Heinrichs-Graham

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

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  17. Oscillatory brain dynamics underlying affective face processing.Social cognitive and affective neuroscience · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tony W WilsonDepartment of Neurological Sciences, University of Nebraska Medical Center (UNMC), Omaha, NE, USA.
Timothy J McDermottCenter for Magnetoencephalography, UNMC, Omaha, NE 68198, USA.
Mackenzie S MillsCenter for Magnetoencephalography, UNMC, Omaha, NE 68198, USA.
Nathan M CoolidgeCenter for Magnetoencephalography, UNMC, Omaha, NE 68198, USA.
Elizabeth Heinrichs-GrahamDepartment of Neurological Sciences, University of Nebraska Medical Center (UNMC), Omaha, NE, USA.

Funding

Neurophysiological markers of HAND and the impact of aging: Evidence from MEGR01MH103220 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2014 to 2018
$2.5M
NIMH NIH HHS R01 MH103220
6 · The paper itself

Abstract

Transcranial direct-current stimulation (tDCS) is now a widely used method for modulating the human brain, but the resulting physiological effects are not understood. Recent studies have combined magnetoencephalography (MEG) with simultaneous tDCS to evaluate online changes in occipital alpha and gamma oscillations, but no study to date has quantified the offline (i.e., after tDCS) alterations in these responses. Thirty-five healthy adults received active or sham anodal tDCS to the occipital cortices, and then completed a visual stimulation paradigm during MEG that is known to elicit robust gamma and alpha oscillations. The resulting MEG data were imaged and peak voxel time series were extracted to evaluate tDCS effects. We found that tDCS to the occipital increased the amplitude of local gamma oscillations, and basal alpha levels during the baseline. tDCS was also associated with network-level effects, including increased gamma oscillations in the prefrontal cortex, parietal, and other visual attention regions. Finally, although tDCS did not modulate peak gamma frequency, this variable was inversely correlated with gamma amplitude, which is consistent with a GABA-gamma link. In conclusion, tDCS alters gamma oscillations and basal alpha levels. The net offline effects on gamma activity are consistent with the view that anodal tDCS decreases local GABA.

Indexed as

Brain MappingAdultAlpha RhythmFemaleFunctional LateralityGamma RhythmHumansMagnetic Resonance ImagingMagnetoencephalographyMaleOccipital LobePhotic StimulationTime FactorsTranscranial Direct Current StimulationYoung Adult

Identifiers

PMID28334214
PMCPMC5907344

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.