Evidence map›Paper›PMID 28333945›Full record

ArticlePloS one2017

Environmental reservoirs of pathogenic mycobacteria across the Ethiopian biogeographical landscape.

Hayley C King, Tanya Khera-Butler, Phillip James, Brian B Oakley, Girume Erenso, Abraham Aseffa, Rob Knight, Elizabeth M Wellington, Orin Courtenay

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. The clinical and epidemiological landscape ofFrontiers in cellular and infection microbiology · 2026
    Pooled it
  2. Article
  3. A microbial safari: finding evidence ofMicrobiology spectrum · 2026
    Article
  4. Review
  5. Spatiotemporal distribution ofEmerging microbes & infections · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Insights into the ancestry evolution of theNAR genomics and bioinformatics · 2021
    Article
  17. Article
  18. Article
  19. DoesVeterinary medicine international · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Hayley C KingSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.
Tanya Khera-ButlerSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.
Phillip JamesSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.
Brian B OakleyCollege of Veterinary Medicine, Western University of Health Sciences, Pomona, California, United States of America.
Girume ErensoSt. Paul's Hospital Millennium Medical College, Department of Microbiology, Immunology and Parasitology, Addis Ababa, Ethiopia.
Abraham AseffaArmauer Hansen Research Institute (AHRI), ALERT Campus, Addis Ababa, Ethiopia.
Rob KnightDepartment of Pediatrics and Department of Computer Science, University of California, San Diego, California, United States of America.
Elizabeth M WellingtonSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.
Orin CourtenaySchool of Life Sciences, University of Warwick, Coventry, United Kingdom.
University of Warwick · GBArmauer Hansen Research Institute · ETSt. Paul's Hospital Millennium Medical College · ETUniversity of California, San Diego · USWestern University of Health Sciences · US

Funding

Biotechnology and Biological Sciences Research Council BB/L027801/1Biotechnology and Biological Sciences Research Council BB/N004655/1
6 · The paper itself

Abstract

The Mycobacterium genus comprises over one-hundred-and-fifty recognised species, the majority of which reside in the environment and many of which can be pathogenic to mammals. Some species of environmental mycobacteria may interfere with BCG vaccination efficacy and in tuberculin test interpretation. Examining biogeographic trends in the distribution of members of the mycobacteria across a number of physicochemical and spatial gradients in soil and water environments across Ethiopia using oligotyping identified differential distributions of pathogenic and significant species. The tuberculosis complex was identified in more than 90% of water samples and taxonomic groups implicated in lower BCG vaccine efficiency were core in both soil and water Mycobacterium communities. A reservoir of Mycobacterium bovis was identified in water, with up to 7.3×102 genome equivalents per ml. Elevation, temperature, habitat and vegetation type were important predictors of both soil and water Mycobacterium communities. These results represent the first step in understanding the potential risk of exposure to environmental mycobacteria that may undermine efforts to reduce disease incidence.

Indexed as

AltitudeBiodiversityDisease ReservoirsEnvironmentEthiopiaHumansMycobacteriumMycobacterium bovisSoil MicrobiologyWater Microbiology

Identifiers

PMID28333945
PMCPMC5363844
OpenAlexW2602527913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.