Evidence map›Paper›PMID 28333157›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2017

Consensus approach to nasal high-flow therapy in neonates.

B A Yoder, B Manley, C Collins, K Ives, A Kugelman, A Lavizzari, M McQueen

Registry-linked trialAbstract readConsensus Statement
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03548324 (Enteral Nutrition Tolerance and Non-invasive Respiratory Support in Preterm Infants), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03548324 nacompletednot on this mapstarted 2019, after this paper: background citation

Enteral Nutrition Tolerance and Non-invasive Respiratory Support in Preterm Infants

TypeinterventionalSponsorUniversity of Turin, ItalyRan2019 to 2021Enrolled280ConditionsVery Low Birth Weight Infant, Respiratory Distress Syndrome in Premature Infant, Enteral Feeding IntoleranceArmsHHHFNC, NCPAP
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Interprofessional education involving respiratory therapists: A narrative review of implementation models, educational outcomes, and research gaps.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 5 countries.

B A YoderDepartment of Pediatrics-Neonatology, University of Utah School of Medicine, Salt Lake City, UT, USA.
B ManleyThe Royal Women's Hospital, Melbourne, and the Department of Obstetrics and Gynaecology, The University of Melbourne, Melbourne, VIC, Australia.
C CollinsMercy Hospital for Women, Melbourne, VIC, Australia.
K IvesJohn Radcliffe Hospital, Oxford, UK.
A KugelmanBnai Zion Medical Center, Rappaport Faculty of Medicine, Technion, Haifa, Israel.
A LavizzariFondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.
M McQueenDivision of Neonatology, Banner Health System, Phoenix, AZ, USA.
Banner Health · USBnai Zion Medical Center · ILFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITJohn Radcliffe Hospital · GBMercy Hospital for Women · AURoyal Women's Hospital · AUUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNasal high-flow therapy (nHFT) is commonly used for noninvasive respiratory support in the neonatal intensive care unit. Our objective was to determine which aspects of neonatal nHFT have achieved adequate evidence base to support consensus among experienced clinical investigators, and to document areas lacking consensus to promote future investigations. STUDY

designProspective, modified Delphi collation of tabular queries related to specific aspects of neonatal nHFT. Seven international nHFT clinical researchers were queried regarding approaches to initiation, escalation, weaning and discontinuing nHFT. Completed tables were reviewed independently by each investigator, results clarified and discussed and areas of consensus determined.

resultsConsensus agreement was reached for many aspects of nHFT including: need for adequate heating and humidification, need to prevent nares occlusion, maximum flow rate of 8 l min

conclusionsAmong an experienced group of nHFT clinical researchers, there was general consensus in the approach to neonatal nHFT. Additional randomized studies are indicated to provide better evidence related to several aspects of nHFT, as well as to identify other clinical conditions where nHFT may provide safe, effective noninvasive support.

Indexed as

Continuous Positive Airway PressureDelphi TechniqueHumansInfant, NewbornIntensive Care Units, NeonatalInternational CooperationProspective StudiesRespiratory Distress Syndrome, Newborn

Identifiers

PMID28333157
OpenAlexW2600763608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.