ArticleCell death & disease2017
Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase.
Article in Cell death & disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Regulation of differentiation and generation of osteoclasts in rheumatoid arthritis.Frontiers in immunology · 2022Pooled it
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- NAPRT-mediated deamidated NAD biosynthesis enhances colon tissue resiliency and suppresses tumorigenesis.Nature communications · 2026Article
- A sensory and motor neuropathy caused by a genetic variant ofScience advances · 2025Article
- Molecular Profiling of Inflammatory and Myofibroblast Cancer-Associated Fibroblast Subtypes Derived from Human Pancreatic Stellate Cells Using Machine Learning-Based Label-Free Raman Spectroscopy.Biomaterials research · 2025Article
- Early life microbiome disbalance impacts neuroendocrine outcomes in pre-pubertal mice in a sexually dimorphic manner.Frontiers in microbiology · 2025Article
- Serum visfatin in multiple sclerosis: distinct profiles in healthy controls, naive patients, and treated RRMS.Frontiers in immunology · 2025Article
- Protein Acetylation and NAD+ Homeostasis in Aging Muscle.Advances in experimental medicine and biology · 2025Review
- Cryptic phosphoribosylase activity of NAMPT restricts the virion incorporation of viral proteins.Nature metabolism · 2024Article
- Review
- eNAMPT is a novel therapeutic target for mitigation of coronary microvascular disease in type 2 diabetes.Diabetologia · 2024Article
- The Interferon-inducible NAMPT acts as a protein phosphoribosylase to restrict viral infection.bioRxiv : the preprint server for biology · 2023Article
- NADCellular & molecular immunology · 2023Article
- The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice.Nature communications · 2023Article
- Interactions between Intestinal Homeostasis and NADNutrients · 2023Review
- Review
- Redox regulation of the immune response.Cellular & molecular immunology · 2022Review
- Metabolic control of histone acetylation for precise and timely regulation of minor ZGA in early mammalian embryos.Cell discovery · 2022Article
- Targeting Danger Signals to Rescue Fibrosis.American journal of respiratory cell and molecular biology · 2022Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
Nicotinamide phosphoribosyltransferase (NAMPT) is a pleiotropic protein implicated in the pathogenesis of acute respiratory distress syndrome, aging, cancer, coronary heart diseases, diabetes, nonalcoholic fatty liver disease, obesity, rheumatoid arthritis, and sepsis. However, the underlying molecular mechanisms of NAMPT in these physiological and pathological processes are not fully understood. Here, we provide experimental evidence that a Nampt gene homozygous knockout (Nampt
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.