Evidence map›Paper›PMID 28333122›Full record

ArticleGenes2017

Differences in the Bacteriome of Smokeless Tobacco Products with Different Oral Carcinogenicity: Compositional and Predicted Functional Analysis.

Nezar Noor Al-Hebshi, Fahd Ali Alharbi, Mohammed Mahri, Tsute Chen

Open access · goldAbstract read
In one paragraph

Article in Genes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Viable, Multi-Drug-Resistant Bacteria Recovered from E-Liquids Used with Commercial Electronic Cigarettes.International journal of environmental research and public health · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Microbial Changes Associated With Oral Cavity Cancer Progression.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Microbiology of the American Smokeless Tobacco.Applied microbiology and biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Nezar Noor Al-HebshiDepartment of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, 45142 Jazan, Saudi Arabia. alhebshi@temple.edu.
Fahd Ali AlharbiOtolaryngology-Head and Neck Surgery Department, Faculty of Medicine, Jazan University, 45142 Jazan, Saudi Arabia. fahdalharbi3@gmail.com.
Mohammed MahriDepartment of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, 45142 Jazan, Saudi Arabia. dr.m.mahri@hotmail.com.
Tsute ChenDepartment of Microbiology, Forsyth Institute, Cambridge, MA 02142, USA. tchen@forsyth.org.
Jazan University · SATemple University · US

Funding

Mouse Oral Microbiome DatabaseR37DE016937 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI DEWHIRST, FLOYD E · 2011 to 2020
$8.6M
NIDCR NIH HHS R37 DE016937
6 · The paper itself

Abstract

Smokeless tobacco (ST) products vary significantly in their oral carcinogenicity. Much is known about the differences in the chemical, but not the bacterial, constituents of these products. In this study, we explored the composition and function of the bacteriome in ST products from four countries using quantitative polymerase chain reaction (qPCR) and 16S rRNA-based next generation sequencing. The bacterial load (16S rRNA copies/gram) was lowest in Swedish snus (3.4 × 10⁶) and highest in Yemeni shammah (6.6 × 10

Indexed as

bacteriabacteriomecarcinomamicrobiomemouthsmokelesssnufftobacco

Identifiers

PMID28333122
PMCPMC5406853
OpenAlexW2592424082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.