Evidence map›Paper›PMID 28333113›Full record

ArticleMolecules (Basel, Switzerland)2017

Silane Modified Diopside for Improved Interfacial Adhesion and Bioactivity of Composite Scaffolds.

Cijun Shuai, Chenying Shuai, Pei Feng, Youwen Yang, Yong Xu, Tian Qin, Sheng Yang, Chengde Gao, Shuping Peng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cijun ShuaiState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China. shuai@csu.edu.cn.
Chenying ShuaiState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China. shuaichenying@csu.edu.cn.
Pei FengState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China. fengpei@csu.edu.cn.
Youwen YangState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China. yangyouwen@csu.edu.cn.
Yong XuState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China. xuyong2927@csu.edu.cn.
Tian QinState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China. qintian@csu.edu.cn.
Sheng YangHuman Reproduction Center, Shenzhen Hospital of Hongkong University, Shenzhen 518053, China. tobyys2000@aliyun.com.
Chengde GaoState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China. gaochengde@csu.edu.cn.
Shuping PengThe Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha 410008, China. gaochengde@csu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diopside (DIOP) was introduced into polyetheretherketone/polyglycolicacid (PEEK/PGA) scaffolds fabricated via selective laser sintering to improve bioactivity. The DIOP surface was then modified using a silane coupling agent, 3-glycidoxypropyltrimethoxysilane (KH570), to reinforce interfacial adhesion. The results showed that the tensile properties and thermal stability of the scaffolds were significantly enhanced. It could be explained that, on the one hand, the hydrophilic group of KH570 formed an organic covalent bond with the hydroxy group on DIOP surface. On the other hand, there existed relatively high compatibility between its hydrophobic group and the biopolymer matrix. Thus, the ameliorated interface interaction led to a homogeneous state of DIOP dispersion in the matrix. More importantly, an in vitro bioactivity study demonstrated that the scaffolds with KH570-modified DIOP (KDIOP) exhibited the capability of forming a layer of apatite. In addition, cell culture experiments revealed that they had good biocompatibility compared to the scaffolds without KDIOP. It indicated that the scaffolds with KDIOP possess potential application in tissue engineering.

Indexed as

Cell LineHumansSilanesSilicic AcidSurface PropertiesdiopsideSilanesSilicic Acidbioactivitydiopsideinterface adhesionscaffoldssilane coupling agent

Identifiers

PMID28333113
PMCPMC6153932

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.