Evidence map›Paper›PMID 28333102›Full record

ArticleInternational journal of molecular sciences2017

Biological Effect of Licochalcone C on the Regulation of PI3K/Akt/eNOS and NF-κB/iNOS/NO Signaling Pathways in H9c2 Cells in Response to LPS Stimulation.

Sara Franceschelli, Mirko Pesce, Alessio Ferrone, Daniela Maria Pia Gatta, Antonia Patruno, Maria Anna De Lutiis, José Luis Quiles, Alfredo Grilli, Mario Felaco, Lorenza Speranza

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Pharmacological Effects and Underlying Mechanisms of Licorice-Derived Flavonoids.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  5. Acetyl-11-Keto-Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  6. Article
  7. Licorice (OncoTargets and therapy · 2022
    Review
  8. Carnosol Attenuates LPS-Induced Inflammation of Cardiomyoblasts by Inhibiting NF-Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  9. Plants (Basel, Switzerland) · 2021
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Natural Chalcones in Chinese Materia Medica: Licorice.Evidence-based complementary and alternative medicine : eCAM · 2020
    Review
  20. Effect of Curcumol on the Fenestrae of Liver Sinusoidal Endothelial Cells Based on NF-Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Sara FranceschelliDepartment of Medicine and Science of Aging, University "G. D'Annunzio", Chieti 66100, Italy. s.franceschelli@unich.it.
Mirko PesceDepartment of Psychological, Health and Territorial Sciences, University "G. D'Annunzio", Chieti 66100, Italy. alessio.ferrone@yahoo.it.
Alessio FerroneDepartment of Medicine and Science of Aging, University "G. D'Annunzio", Chieti 66100, Italy. danielagatta@unich.it.
Daniela Maria Pia GattaDepartment of Medicine and Science of Aging, University "G. D'Annunzio", Chieti 66100, Italy. antonia.patruno@unich.it.
Antonia PatrunoDepartment of Medicine and Science of Aging, University "G. D'Annunzio", Chieti 66100, Italy. maria.delutiis@unich.it.
Maria Anna De LutiisDepartment of Medicine and Science of Aging, University "G. D'Annunzio", Chieti 66100, Italy. mfelaco@unich.it.
José Luis QuilesDepartment of Physiology, Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Centre, University of Granada, Granada 18071, Spain. lorenza.speranza@unich.it.
Alfredo GrilliDepartment of Psychological, Health and Territorial Sciences, University "G. D'Annunzio", Chieti 66100, Italy. mirkopesce@unich.it.
Mario FelacoDepartment of Medicine and Science of Aging, University "G. D'Annunzio", Chieti 66100, Italy. algrilli@unich.it.
Lorenza SperanzaDepartment of Medicine and Science of Aging, University "G. D'Annunzio", Chieti 66100, Italy. jlquiles@ugr.es.
University of Chieti-Pescara · ITUniversidad de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyphenols compounds are a group molecules present in many plants. They have antioxidant properties and can also be helpful in the management of sepsis. Licochalcone C (LicoC), a constituent of

Indexed as

AnimalsAnti-Inflammatory AgentsCell LineChalconesIntercellular Adhesion Molecule-1LipopolysaccharidesNF-kappa BNitric OxideNitric Oxide Synthase Type IINitric Oxide Synthase Type IIIPhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase InhibitorsProto-Oncogene Proteins c-aktRatsSignal TransductionAnti-Inflammatory AgentsChalconesIntercellular Adhesion Molecule-1licochalcone CLipopolysaccharidesNF-kappa BNitric OxideNitric Oxide Synthase Type IINitric Oxide Synthase Type IIIPhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase InhibitorsProto-Oncogene Proteins c-aktadhesion moleculeAktcardiomyocytesinflammationlicochalcone Cnitric oxidenuclear factor-κB

Identifiers

PMID28333102
PMCPMC5412276
OpenAlexW2601733070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.