Evidence map›Paper›PMID 28333079›Full record

ArticleMarine drugs2017

Marine Cyclic Guanidine Alkaloids Monanchomycalin B and Urupocidin A Act as Inhibitors of TRPV1, TRPV2 and TRPV3, but not TRPA1 Receptors.

Yuliya Korolkova, Tatyana Makarieva, Kseniya Tabakmakher, Larisa Shubina, Ekaterina Kudryashova, Yaroslav Andreev, Irina Mosharova, Hyi-Seung Lee, Yeon-Ju Lee, Sergey Kozlov

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. TRPV3 Ion Channel: From Gene to Pharmacology.International journal of molecular sciences · 2023
    Review
  8. TRPV3: Structure, Diseases and Modulators.Molecules (Basel, Switzerland) · 2023
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. TRPV2 channel as a possible drug target for the treatment of heart failure.Laboratory investigation; a journal of technical methods and pathology · 2020
    Review
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Yuliya KorolkovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Street, 16/10, Moscow 117997, Russia. july@mx.ibch.ru.
Tatyana MakarievaG.B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC), Russian Academy of Sciences, Prospect 100 let Vladivostoku, 159, Vladivostok 690022, Russia. makarieva@piboc.dvo.ru.
Kseniya TabakmakherG.B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC), Russian Academy of Sciences, Prospect 100 let Vladivostoku, 159, Vladivostok 690022, Russia. dark_xen@mail.ru.
Larisa ShubinaG.B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC), Russian Academy of Sciences, Prospect 100 let Vladivostoku, 159, Vladivostok 690022, Russia. shubina@piboc.dvo.ru.
Ekaterina KudryashovaG.B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC), Russian Academy of Sciences, Prospect 100 let Vladivostoku, 159, Vladivostok 690022, Russia. catrinog.81@mail.ru.
Yaroslav AndreevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Street, 16/10, Moscow 117997, Russia. ay@land.ru.
Irina MosharovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Street, 16/10, Moscow 117997, Russia. mosharova@mail.ru.
Hyi-Seung LeeKorea Institute of Ocean Science & Technology, Marine Natural Products Laboratory, Ansan 426-744, Korea. hslee@kiost.ac.kr.
Yeon-Ju LeeKorea Institute of Ocean Science & Technology, Marine Natural Products Laboratory, Ansan 426-744, Korea. yjlee@kiost.ac.kr.
Sergey KozlovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Street, 16/10, Moscow 117997, Russia. serg@ibch.ru.
Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences · RUInstitute of Bioorganic Chemistry · RUKorea Institute of Ocean Science and Technology · KRSechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine sponges contain a variety of low-molecular-weight compounds including guanidine alkaloids possessing different biological activities. Monanchomycalin B and urupocidin A were isolated from the marine sponge

Indexed as

AlkaloidsAnimalsAquatic OrganismsGuanidineGuanidinesHumansMicePoriferaRatsStructure-Activity RelationshipTRPV Cation ChannelsAlkaloidsGuanidineGuanidinesTRPV Cation Channelsurupocidin Aguanidine alkaloidsMonanchora pulchraspongeTRPA1TRPV1TRPV2TRPV3

Identifiers

PMID28333079
PMCPMC5408233
OpenAlexW2598352533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.