Evidence map›Paper›PMID 28332980›Full record

ArticleeLife2017

A receptor and neuron that activate a circuit limiting sucrose consumption.

Ryan M Joseph, Jennifer S Sun, Edric Tam, John R Carlson

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Connectomic mapping of pharyngeal and gut sensory circuits in adultbioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Nutrient Sensing via Gut inInternational journal of molecular sciences · 2022
    Review
  14. A functional division ofProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Recent advances in the genetic basis of taste detection in Drosophila.Cellular and molecular life sciences : CMLS · 2020
    Review
  20. The Structure and Function of Ionotropic Receptors inFrontiers in molecular neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryan M JosephDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States.ORCID 0000-0001-8203-7154
Jennifer S SunDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States.ORCID 0000-0002-4274-0504
Edric TamDepartment of Biomedical Engineering, Yale University, New Haven, United States.
John R CarlsonDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States.ORCID 0000-0002-0244-5180

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007499 · NIGMS · YALE UNIVERSITY · PI CARLSON, JOHN R, REINKE, VALERIE J · 1985 to 2022
$13.9M
ANALYSIS OF ODORANT RECEPTOR GENESR01DC004729 · NIDCD · YALE UNIVERSITY · PI John R Carlson · 2001 to 2026
$9.2M
GENETIC AND MOLECULAR ANALYSIS OF OLFACTIONR01DC002174 · NIDCD · YALE UNIVERSITY · PI CARLSON, JOHN R · 1994 to 2024
$8.0M
Analysis of a large family of taste receptorsR01DC011697 · NIDCD · YALE UNIVERSITY · PI John R Carlson · 2011 to 2026
$5.5M
NIDCD NIH HHS R01 DC002174NIDCD NIH HHS R01 DC004729NIDCD NIH HHS R01 DC011697NIGMS NIH HHS T32 GM007499
6 · The paper itself

Abstract

The neural control of sugar consumption is critical for normal metabolism. In contrast to sugar-sensing taste neurons that promote consumption, we identify a taste neuron that limits sucrose consumption in

Indexed as

AnimalsCalciumDisaccharidesDrosophila melanogasterDrosophila ProteinsEatingFeedback, PhysiologicalFeeding BehaviorGene ExpressionGlycerolMonosaccharidesMutationNeuronsOptical ImagingReceptors, G-Protein-CoupledSucroseCalciumDisaccharidesDrosophila ProteinsGlycerolMonosaccharidesReceptors, G-Protein-CoupledSucrosechromosomesdietary regulationD. melanogasterfeeding inhibitiongenesgustatory receptorionotropic receptorneurosciencepharynxtaste

Identifiers

PMID28332980
PMCPMC5388533

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.