Evidence map›Paper›PMID 28332920›Full record

ArticleNeuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition2018

Terminal decline of episodic memory and perceptual speed in a biracial population.

Robert S Wilson, Kumar B Rajan, Lisa L Barnes, Willemijn Jansen, Priscilla Amofa, Jennifer Weuve, Denis A Evans

Open access · greenAbstract readComparative Study
In one paragraph

Article in Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Robert S Wilsona Rush Alzheimer's Disease Center, Department of Neurological Sciences, Department of Behavioral Sciences , Rush University Medical Center , Chicago , IL , USA.
Kumar B Rajanb Rush Institute for Healthy Aging, Department of Internal Medicine , Rush University Medical Center , Chicago , IL , USA.
Lisa L Barnesa Rush Alzheimer's Disease Center, Department of Neurological Sciences, Department of Behavioral Sciences , Rush University Medical Center , Chicago , IL , USA.
Willemijn Jansenc Department of Psychiatry & Neuropsychology , Maastricht University , Maastricht , the Netherlands.
Priscilla Amofad Rush Alzheimer's Disease Center , Rush University Medical Center , Chicago , IL , USA.
Jennifer Weuvee Department of Epidemiology, School of Public Health , Boston University , Boston , MA , USA.
Denis A Evansb Rush Institute for Healthy Aging, Department of Internal Medicine , Rush University Medical Center , Chicago , IL , USA.
Rush University Medical Center · USBoston University · USMaastricht University · NL

Funding

SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LEURGANS, SUE E. · 1991 to 2020
$49.1M
UC Davis Alzheimer's Disease Core CenterP30AG010129 · NIA · UNIVERSITY OF CALIFORNIA DAVIS · PI DECARLI, CHARLES · 1991 to 2020
$28.3M
Risk Factors for Incident Alzheimer's Disease in a Biracial CommunityR01AG011101 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI EVANS, DENIS A · 1993 to 2010
$24.7M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
Racial Differences in Late-Life Cognitive Decline and Risk of Alzheimer's DiseaseRF1AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2016 to 2019
$6.6M
Nonlinear Models of Cognition Preceding AD in a Biracial Population SampleR01AG051635 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RAJAN, KUMAR B. · 2016 to 2020
$1.5M
NIA NIH HHS P30 AG010129NIA NIH HHS R01 AG011101NIA NIH HHS R01 AG022018NIA NIH HHS R01 AG051635NIA NIH HHS RF1 AG022018
6 · The paper itself

Abstract

We compared trajectories of terminal cognitive decline in older Black (n = 3372) and White (n = 1756) persons from a defined population who completed tests of episodic memory and perceptual speed at 3-year intervals for up to 18 years. During a mean of 9.9 years of observation, 1608 Black persons and 902 White persons died. Preterminal decline of episodic memory did not differ by race. Terminal episodic memory decline began earlier in Black persons (mean of 4.3 years before death) than in White persons (mean = 3.9 years) and progressed more slowly. By contrast, terminal decline of perceptual speed began earlier in White persons (mean = 5.0 years) than in Black persons (mean = 4.5 years). Rate of perceptual speed decline was more rapid in White persons than in Black persons in both the preterminal and terminal periods. The results indicate that terminal cognitive decline occurs in Black persons but suggest that the rate of cognitive decline during the terminal period is less rapid in Black persons than in White persons.

Indexed as

Memory, EpisodicAgedBlack or African AmericanChicagoCognitive AgingCognitive DysfunctionDisease ProgressionFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleTime FactorsWhite Peopleepisodic memorylongitudinal studyperceptual speedracial differencesTerminal decline

Identifiers

PMID28332920
PMCPMC5928786
OpenAlexW2603418826

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.