ArticleScientific reports2017
Cell cycle arrest and biochemical changes accompanying cell death in harmful dinoflagellates following exposure to bacterial algicide IRI-160AA.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 44 citations in OpenAlex.
- Selenite reduces algal reactive oxygen species accumulation and enhances algal resistance to a bacterial pathogen.ISME communications · 2026Article
- Tetrapeptide from microbial coculture exhibiting a unique algicidal mechanism against Alexandrium fundyense.Scientific reports · 2025Article
- Review
- Molecular Insights into the Synergistic Effects of Putrescine and Ammonium on Dinoflagellates.International journal of molecular sciences · 2024Article
- Flavobacterial exudates disrupt cell cycle progression and metabolism of the diatom Thalassiosira pseudonana.The ISME journal · 2022Article
- A Novel Algicidal Bacterium and Its Effects against the Toxic DinoflagellateMicrobiology spectrum · 2022Article
- Metabolomic Insights of the Effects of Bacterial Algicide IRI-160AA on DinoflagellateMetabolites · 2022Article
- Algicidal Bacteria: A Review of Current Knowledge and Applications to Control Harmful Algal Blooms.Frontiers in microbiology · 2022Review
- Identification of a Metacaspase Gene in the Bloom-Forming Dinoflagellate Prorocentrum minimum and its Putative Function Involved in Programmed Cell Death.Current microbiology · 2021Article
- Bacterial Quorum-Sensing Signal Arrests Phytoplankton Cell Division and Impacts Virus-Induced Mortality.mSphere · 2021Article
- Effects of a bacteria-produced algicide on non-target marine invertebrate species.Scientific reports · 2021Article
- Biochemical and Physiological Responses of HarmfulFrontiers in microbiology · 2021Article
- Mitochondrial Neuroglobin Is Necessary for Protection Induced by Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cells in Astrocytic Cells Subjected to Scratch and Metabolic Injury.Molecular neurobiology · 2019Article
- Associated Bacteria Affect Sexual Reproduction by Altering Gene Expression and Metabolic Processes in a Biofilm Inhabiting Diatom.Frontiers in microbiology · 2019Article
- Small Polar Molecules: A Challenge in Marine Chemical Ecology.Molecules (Basel, Switzerland) · 2018Article
- The chemical cue tetrabromopyrrole induces rapid cellular stress and mortality in phytoplankton.Scientific reports · 2018Article
- Algicidal Activity of Novel Marine Bacterium Paracoccus sp. Strain Y42 against a Harmful Algal-Bloom-Causing Dinoflagellate, Prorocentrum donghaiense.Applied and environmental microbiology · 2018Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteria may play a role in regulating harmful algal blooms, but little is known about the biochemical and physiological changes associated with cell death induced by algicidal bacteria. Previous work characterized an algicidal exudate (IRI-160AA) produced by Shewanella sp. IRI-160 that is effective against dinoflagellates, while having little to no effect on other phytoplankton species in laboratory culture experiments. The objective of this study was to evaluate biochemical changes associated with cell death and impacts on the cell cycle in three dinoflagellate species (Prorocentrum minimum, Karlodinium veneficum and Gyrodinium instriatum) after exposure to IRI-160AA. In this study, IRI-160AA induced cell cycle arrest in all dinoflagellates examined. Several indicators for programmed cell death (PCD) that are often observed in phytoplankton in response to a variety of stressors were also evaluated. Cell death was accompanied by significant increases in DNA degradation, intra- and extracellular ROS concentrations and DEVDase (caspase-3 like) protease activity, which have been associated with PCD in other phytoplankton species. Overall, results of this investigation provide strong evidence that treatment with the bacterial algicide, IRI-160AA results in cell cycle arrest and induces biochemical changes consistent with stress-related cell death responses observed in other phytoplankton.
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