ArticleNature communications2017
Natural variation in CTB4a enhances rice adaptation to cold habitats.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers, 2 of them syntheses that pooled it.
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Who cites it
149 citing papers in PubMed, 2 syntheses or guidelines pooled it, 330 citations in OpenAlex.
- Integrated meta-analysis and transcriptomics pinpoint genomic loci and novel candidate genes associated with submergence tolerance in rice.BMC genomics · 2024Pooled it
- Pooled it
- OsERF5 enhances cold tolerance and is associated with GA‑mediated antioxidant defence in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Natural variation in WRKY53 confers cold tolerance at the booting stage between japonica and indica rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Single-Cell and Spatial Omics Technologies in Rice Abiotic Stress Biology: A Methodological Review.International journal of molecular sciences · 2026Review
- Deciphering the genetic basis of nodule number through integrative analysis of host genotype and endophytes.Journal of advanced research · 2026Article
- Temperature regulation in plants: From molecular mechanisms to climate-resilient crop improvement.Journal of integrative plant biology · 2026Review
- Genome and transcriptome analyses reveal parallel altitude adaptation in Chenopodium.Genome biology · 2026Article
- The Rice Cis-Natural Antisense Transcript NAT1850 of Pri-miR1850 Negatively Regulates Cold Tolerance by Repressing NPR3.Plant biotechnology journal · 2026Article
- Discovery of cold tolerance genes and favorable alleles in Kam sweet rice across various growth stages.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- The Pentatricopeptide Repeat Protein OsPPR7 Confers Cold Tolerance at the Booting Stage in Rice by Regulating ABA and ROS Homeostasis.Rice (New York, N.Y.) · 2026Article
- The receptor-like pseudokinase LENG stimulates chilling tolerance in rice by inhibiting the activity of the OsCRPK1-OsGF14d module.Journal of integrative plant biology · 2026Article
- Low Temperature Impacts Root Physiological Characteristics and Related Microbial Community Diversity in the Rhizosphere of Japonica Rice.Microorganisms · 2026Article
- Transcriptome Analysis IdentifiesPlants (Basel, Switzerland) · 2026Article
- Research progress on cold tolerance key genes and mechanisms in four major northern China crops.Frontiers in plant science · 2026Review
- Genome-wide identification of mFrontiers in plant science · 2026Article
- Stage-specific screening reveals differential resilience response to cold stress in rice.PloS one · 2026Article
- Engineering non-coding DNA Elements in Rice: an Elegant Approach To fine-tune Agronomical Advantageous Traits.Rice (New York, N.Y.) · 2025Review
- Protein Post-Translational Modifications in Plant Abiotic Stress Responses.Plants (Basel, Switzerland) · 2025Review
- Identification of miRNAs in Response to Cold Stress in 'Chaling' Common Wild Rice (Life (Basel, Switzerland) · 2025Article
89 more citing papers are in PubMed but not listed here.
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Authors and funding
21 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low temperature is a major factor limiting rice productivity and geographical distribution. Improved cold tolerance and expanded cultivation to high-altitude or high-latitude regions would help meet growing rice demand. Here we explored a QTL for cold tolerance and cloned the gene, CTB4a (cold tolerance at booting stage), encoding a conserved leucine-rich repeat receptor-like kinase. We show that different CTB4a alleles confer distinct levels of cold tolerance and selection for variation in the CTB4a promoter region has occurred on the basis of environmental temperature. The newly generated cold-tolerant haplotype Tej-Hap-KMXBG was retained by artificial selection during temperate japonica evolution in cold habitats for low-temperature acclimation. Moreover, CTB4a interacts with AtpB, a beta subunit of ATP synthase. Upregulation of CTB4a correlates with increased ATP synthase activity, ATP content, enhanced seed setting and improved yield under cold stress conditions. These findings suggest strategies to improve cold tolerance in crop plants.
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