Evidence map›Paper›PMID 28332205›Full record

ArticleThe Journal of physiology2017

Evidence that 5-HT stimulates intracellular Ca

Sindhubarathi Murali, Min Zhang, Colin A Nurse

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. The Carotid Body "Tripartite Synapse": Role of Gliotransmission.Advances in experimental medicine and biology · 2023
    Review
  6. Intra-carotid body inter-cellular communication.Journal of the Royal Society of New Zealand · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sindhubarathi MuraliDepartment of Biology, McMaster University, Hamilton, Ontario, Canada.
Min ZhangDepartment of Biology, McMaster University, Hamilton, Ontario, Canada.
Colin A NurseDepartment of Biology, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-9514-858X
McMaster University · CA

Funding

CIHR MOP 142469
6 · The paper itself

Abstract

key points5-HT is a neuromodulator released from carotid body (CB) chemoreceptor (type I) cells and facilitates the sensory discharge following chronic intermittent hypoxia (CIH). In the present study, we show that, in addition to type I cells, adjacent glial-like type II cells express functional, ketanserin-sensitive 5-HT ABSTRACT: Carotid body (CB) chemoreceptor (type I) cells can synthesize and release 5-HT and increased autocrine-paracrine 5-HT

Indexed as

Action PotentialsCalcium SignalingAnimalsCarbenoxoloneCarotid BodyCells, CulturedChemoreceptor CellsConnexinsEgtazic AcidNerve Tissue ProteinsPurinergic P2Y Receptor AntagonistsRatsRats, WistarSerotoninSerotonin Receptor Agonists1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acidCarbenoxoloneConnexinsEgtazic AcidNerve Tissue Proteinspannexin 1, ratPurinergic P2Y Receptor AntagonistsSerotoninSerotonin Receptor Agonists5-HT2 receptorsketanserinpannexin-1 channels

Identifiers

PMID28332205
PMCPMC5491882
OpenAlexW2603642104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.