Evidence map›Paper›PMID 28332155›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2017

Cerebellopontine angle tumors in young children, displaying cranial nerve deficits, and restricted diffusion on diffusion-weighted imaging: a new clinical triad for atypical teratoid/rhabdoid tumors.

Joel S Katz, Pier Paolo Peruzzi, Christopher R Pierson, Jonathan L Finlay, Jeffrey R Leonard

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In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Joel S KatzDivision of Pediatric Neurosurgery, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Pier Paolo PeruzziDivision of Pediatric Neurosurgery, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Christopher R PiersonDepartment of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Jonathan L FinlayDepartment of Neurosurgery, Ohio State University, Columbus, OH, USA.
Jeffrey R LeonardDivision of Pediatric Neurosurgery, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA. Jeffrey.Leonard@nationwidechildrens.org.
The Ohio State University · USGrant Medical Center · USNationwide Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atypical teratoid/rhabdoid tumors (AT/RT) of the central nervous system (CNS) are rare, highly malignant neoplasms that carry a poor prognosis. Even with prompt diagnosis, gross total resection and early initiation of intensive adjuvant therapy, the majority of patients will succumb within 9-12 months of diagnosis. The CPA location in children harbors lesions along a wide spectrum varying from benign to highly malignant. Imaging features of lesions within the CPA that aid the diagnostic process will help to initiate early treatment in higher-grade lesions. We report three cases, in very young children, all with cranial nerve deficits, who displayed CPA lesions with restricted diffusion on diffusion-weighted imaging (DWI) with pathology confirming AT/RT. We propose that in young children with a CPA tumor diffusion-weighted imaging should be routinely evaluated to aid in prompt management. In addition, the diagnosis of AT/RT should be highly suggestive in infants presenting with cranial nerve findings as well as DWI restricted diffusion within the CPA.

Indexed as

Diffusion Magnetic Resonance ImagingChild, PreschoolCranial NervesFemaleHumansInfantMaleNeuroma, AcousticRhabdoid TumorTeratomaAtypical teratoid rhabdoid tumorCerebellopontine angleDiffuse-weighted imaging

Identifiers

PMID28332155
OpenAlexW2599945807

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.