Evidence map›Paper›PMID 28332111›Full record

ReviewSports medicine (Auckland, N.Z.)2017

Practical Issues in Evidence-Based Use of Performance Supplements: Supplement Interactions, Repeated Use and Individual Responses.

Louise M Burke

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Sports medicine (Auckland, N.Z.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05916352 (The Effect of Caffeine Supplementation on Blood Lactate Level, Performance and Post-Training Fatigue in Elite Basketball Players), which is not on this map. Cited by 53 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05916352 nacompletednot on this mapstarted 2022, after this paper: background citation

The Effect of Caffeine Supplementation on Blood Lactate Level, Performance and Post-Training Fatigue in Elite Basketball Players

TypeinterventionalSponsorCyprus International UniversityRan2022 to 2023Enrolled50ConditionsSportive Performance, CaffeineArmsCaffeine Supplement
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 13 syntheses or guidelines pooled it.

  1. Pooled it
  2. Sport supplementation in competitive swimmers: a systematic review with meta-analysis.Journal of the International Society of Sports Nutrition · 2025
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  13. Acute caffeine supplementation in combat sports: a systematic review.Journal of the International Society of Sports Nutrition · 2018
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  18. Caffeine, but not paracetamol (acetaminophen), enhances muscular endurance, strength, and power.Journal of the International Society of Sports Nutrition · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Louise M BurkeSports Nutrition, Australian Institute of Sport, PO Box 176, Belconnen, ACT, 2616, Australia. louise.burke@ausport.gov.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current sports nutrition guidelines recommend that athletes only take supplements following an evidence-based analysis of their value in supporting training outcomes or competition performance in their specific event. While there is sound evidence to support the use of a few performance supplements under specific scenarios (creatine, beta-alanine, bicarbonate, caffeine, nitrate/beetroot juice and, perhaps, phosphate), there is a lack of information around several issues needed to guide the practical use of these products in competitive sport. First, there is limited knowledge around the strategy of combining the intake of several products in events in which performance benefits are seen with each product in isolation. The range in findings from studies involving combined use of different combinations of two supplements makes it difficult to derive a general conclusion, with both the limitations of individual studies and the type of sporting event to which the supplements are applied influencing the potential for additive, neutral or counteractive outcomes. The repeated use of the same supplement in sports involving two or more events within a 24-h period is of additional interest, but has received even less attention. Finally, the potential for individual athletes to respond differently, in direction and magnitude, to the use of a supplement seems real, but is hard to distinguish from normal day to day variability in performance. Strategies that can be used in research or practice to identify whether individual differences are robust include repeat trials, and the collection of data on physiological or genetic mechanisms underpinning outcomes.

Indexed as

Athletic PerformanceDietary SupplementsPerformance-Enhancing SubstancesAthletesEvidence-Based MedicineHumansSportsPerformance-Enhancing Substances

Identifiers

PMID28332111
PMCPMC5371635

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.