Evidence map›Paper›PMID 28332020›Full record

ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2017

Temperature effects on the activity, shape, and storage of platelets from 13-lined ground squirrels.

Scott Cooper, Sarah Lloyd, Anthony Koch, Xingxing Lin, Katie Dobbs, Thomas Theisen, Matt Zuberbuehler, Kaley Bernhardt, Michael Gyorfi, Tanner Tenpas and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Platelets from 13-lined ground squirrels are resistant to cold storage lesions.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2023
    Article
  3. Hibernation and hemostasis.Frontiers in physiology · 2023
    Review
  4. Reversible thrombocytopenia during hibernation originates from storage and release of platelets in liver sinusoids.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2021
    Article
  5. Cardiovascular resistance to thrombosis in 13-lined ground squirrels.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Scott CooperBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA. scooper@uwlax.edu.ORCID http://orcid.org/0000-0002-2555-6457
Sarah LloydBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Anthony KochBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Xingxing LinBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Katie DobbsBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Thomas TheisenBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Matt ZuberbuehlerBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Kaley BernhardtBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Michael GyorfiBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Tanner TenpasBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Skyler HyingBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Sarah MortimerBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Christine LamontBiology Department, University of Wisconsin-La Crosse, 1725 State St., La Crosse, WI, 54601, USA.
Marcus LehmannChemical and Biological Engineering Department, Colorado School of Mines, Golden, CO, 80401, USA.
Keith NeevesChemical and Biological Engineering Department, Colorado School of Mines, Golden, CO, 80401, USA.
University of Wisconsin–La Crosse · USColorado School of Mines · US

Funding

A Systems Biology Approach to Predicting Bleeding in HemophiliaR01HL120728 · NHLBI · COLORADO SCHOOL OF MINES · PI DI PAOLA, JORGE A, FOGELSON, AARON L · 2014 to 2018
$2.7M
Mechanism of cold storage lesion resistance in hibernating ground squirrel platelets.R15HL093680 · NHLBI · UNIVERSITY OF WISCONSIN LA CROSSE · PI COOPER, SCOTT T · 2008 to 2023
$1.2M
Bead-Based Approach for Combined Mechanical and Pharmacological Treatment of AcutR21NS082933 · NINDS · COLORADO SCHOOL OF MINES · PI HERSON, PACO S, MARR, DAVID WM · 2013 to 2014
$372k
NHLBI NIH HHS R01 HL120728NHLBI NIH HHS R15 HL093680NINDS NIH HHS R21 NS082933
6 · The paper itself

Abstract

The objective of this study is to determine how a hibernating mammal avoids the formation of blood clots under periods of low blood flow. A microfluidic vascular injury model was performed to differentiate the effects of temperature and shear rate on platelet adhesion to collagen. Human and ground squirrel whole blood was incubated at 15 or 37 °C and then passed through a microfluidic chamber over a 250-µm strip of type I fibrillar collagen at that temperature and the shear rates of 50 or 300 s

Indexed as

AnimalsBlood PlateletsCollagenFibrinogenHumansSciuridaeTemperatureTorporvon Willebrand FactorCollagenFibrinogenvon Willebrand FactorCollagenFibrinogenHypothermiaTubulinVon Willebrand factor

Identifiers

PMID28332020
PMCPMC5483195
OpenAlexW2602907264

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.