Evidence map›Paper›PMID 28331977›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2017

Role of plasma membrane-associated AKAPs for the regulation of cardiac I

Claudia Seyler, Daniel Scherer, Christoph Köpple, Martin Kulzer, Sevil Korkmaz, Panagiotis Xynogalos, Dierk Thomas, Ziya Kaya, Eberhard Scholz, Johannes Backs and 3 more

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Claudia SeylerDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany. claudia.seyler@med.uni-heidelberg.de.
Daniel SchererDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany.
Christoph KöppleDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany.
Martin KulzerDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany.
Sevil KorkmazDepartment of Cardiac Surgery, Medical University Hospital Heidelberg, Heidelberg, Germany.
Panagiotis XynogalosDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany.
Dierk ThomasDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany.
Ziya KayaDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany.
Eberhard ScholzDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany.
Johannes BacksDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany.
Christoph KarleDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany.
Hugo A KatusDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany.
Edgar ZitronDepartment of Cardiology, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D-69120, Heidelberg, Germany.
Heidelberg University · DEUniversity Hospital Heidelberg · DEGerman Centre for Cardiovascular Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cardiac I

Indexed as

Adaptor Proteins, Signal TransducingA Kinase Anchor ProteinsAnimalsCell MembraneCHO CellsCricetulusCyclic AMP-Dependent Protein KinasesEnzyme ActivationEnzyme ActivatorsHEK293 CellsHumansImmunoprecipitationIon Channel GatingMembrane PotentialsMicroinjectionsMyocytes, CardiacAdaptor Proteins, Signal TransducingAkap5 protein, ratAkap7 protein, ratA Kinase Anchor ProteinsCyclic AMP-Dependent Protein KinasesEnzyme ActivatorsKCNJ2 protein, ratKir2.2 channelPeptidesPotassium Channels, Inwardly RectifyingAdrenergic signalingAKAPsArrhythmogenesisCardiac IK1 currentPKA

Identifiers

PMID28331977
OpenAlexW2601792643

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.