Evidence map›Paper›PMID 28331783›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2017

Nanoparticle Functionalization and Its Potentials for Molecular Imaging.

Rukmani Thiruppathi, Sachin Mishra, Mathangi Ganapathy, Parasuraman Padmanabhan, Balázs Gulyás

Open access · goldAbstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 167 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Rukmani ThiruppathiLee Kong Chian School of Medicine Nanyang Technological University 59 Nanyang Drive 636921 Singapore; Center for Biotechnology Alagappa College of Technology Anna University Sardar Patel Road Chennai Tamil Nadu 600025 India.
Sachin MishraLee Kong Chian School of Medicine Nanyang Technological University 59 Nanyang Drive 636921 Singapore.
Mathangi GanapathyCenter for Biotechnology Alagappa College of Technology Anna University Sardar Patel Road Chennai Tamil Nadu 600025 India.
Parasuraman PadmanabhanLee Kong Chian School of Medicine Nanyang Technological University 59 Nanyang Drive 636921 Singapore.
Balázs GulyásLee Kong Chian School of Medicine Nanyang Technological University 59 Nanyang Drive 636921 Singapore.
Nanyang Technological University · SGAnna University, Chennai · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functionalization enhances the properties and characteristics of nanoparticles through surface modification, and enables them to play a major role in the field of medicine. In molecular imaging, quality functional images are required with proper differentiation which can be seen with high contrast to obtain viable information. This review article discusses how functionalization enhances molecular imaging and enables multimodal imaging by which images with combination of functions particular to each modality can be obtained. This also explains how nanoparticles interacting at molecular level, when functionalized with molecules can target the cells of interest or substances with high specificity, reducing background signal and allowing simultaneous therapies to be carried out while imaging. Functionalization allows imaging for a prolonged period and enables to track the cells over a period of time. Recent researches and progress in functionalizing the nanoparticles to specifically enhance bioimaging with different modalities and their applications are reviewed in this article.

Indexed as

conjugationfunctionalizationimagingmicroscopynanoparticles

Identifiers

PMID28331783
PMCPMC5357986
OpenAlexW2561796759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.