ReviewMaternal health, neonatology and perinatology2017
Congenital Diaphragmatic hernia - a review.
Review in Maternal health, neonatology and perinatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
111 citing papers in PubMed, 1 synthesis or guideline pooled it, 286 citations in OpenAlex.
- ESR Essentials: imaging of common paediatric pulmonary diseases-practice recommendations by the European Society of Paediatric Radiology.European radiology · 2025Guideline
- Preliminary Report of a Nationwide Prospective Cohort of Congenital Diaphragmatic Hernia in Korea.Journal of Korean medical science · 2026Article
- Correlation of Oxygen Saturation Index with Oxygenation Index in Congenital Diaphragmatic Hernia: in A Secondary Analysis of a Randomized Clinical Trial.The Journal of pediatrics · 2026Article
- Feasibility of invasive neurally-adjusted ventilatory assist in severe congenital diaphragmatic hernia.Journal of perinatology : official journal of the California Perinatal Association · 2026Observational
- Prenatal diagnosis of congenital diaphragmatic hernia with mosaicism of chromosomes 17q and 18q in Iran: a case report.Journal of medical case reports · 2026Article
- Pulmonary T2* quantification of fetuses with congenital diaphragmatic hernia: a retrospective, case-controlled, MRI pilot study.Pediatric research · 2026Article
- Early post-operative hemodynamic recovery in infants with congenital diaphragmatic hernia.European journal of pediatrics · 2026Article
- Article
- Downregulation of pigment epithelium-derived factor increases compensatory lung growth in mice after extended pneumonectomy.Pediatric research · 2026Article
- Follow-up of neonates who received ECMO: how are they doing?European journal of pediatrics · 2026Review
- Risk Stratification of Long-Term Mortality in Infants with Congenital Diaphragmatic Hernia Using the National Health Insurance Service (NHIS) Data.Children (Basel, Switzerland) · 2026Article
- Infant Readmission With Severe Acute Respiratory Failure.NeoReviews · 2026Article
- Asymptomatic diaphragmatic hernia in an elderly patient: case report and review of conservative management.Journal of cardiothoracic surgery · 2025Review
- Extracellular vesicles from mesenchymal stromal cells: an emerging therapy for intractable neonatal disorders.Stem cells translational medicine · 2025Review
- Tension gastrothorax in a late-presenting congenital diaphragmatic hernia: a case report and review of the literature.Journal of surgical case reports · 2025Article
- Article
- Left postpartum diaphragmatic hernia with colonic incarceration: a rare emergency after vaginal delivery.Journal of surgical case reports · 2025Article
- Delayed Presentation of Congenital Diaphragmatic Hernia in the Emergency Department: Case Report.Clinical practice and cases in emergency medicine · 2025Article
- Review
- Cardiac function in children with congenital diaphragmatic hernia: cardiac strain at birth and at 2-5 weeks of age.Frontiers in pediatrics · 2025Article
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenital Diaphragmatic hernia (CDH) is a condition characterized by a defect in the diaphragm leading to protrusion of abdominal contents into the thoracic cavity interfering with normal development of the lungs. The defect may range from a small aperture in the posterior muscle rim to complete absence of diaphragm. The pathophysiology of CDH is a combination of lung hypoplasia and immaturity associated with persistent pulmonary hypertension of newborn (PPHN) and cardiac dysfunction. Prenatal assessment of lung to head ratio (LHR) and position of the liver by ultrasound are used to diagnose and predict outcomes. Delivery of infants with CDH is recommended close to term gestation. Immediate management at birth includes bowel decompression, avoidance of mask ventilation and endotracheal tube placement if required. The main focus of management includes gentle ventilation, hemodynamic monitoring and treatment of pulmonary hypertension followed by surgery. Although inhaled nitric oxide is not approved by FDA for the treatment of PPHN induced by CDH, it is commonly used. Extracorporeal membrane oxygenation (ECMO) is typically considered after failure of conventional medical management for infants ≥ 34 weeks' gestation or with weight >2 kg with CDH and no associated major lethal anomalies. Multiple factors such as prematurity, associated abnormalities, severity of PPHN, type of repair and need for ECMO can affect the survival of an infant with CDH. With advances in the management of CDH, the overall survival has improved and has been reported to be 70-90% in non-ECMO infants and up to 50% in infants who undergo ECMO.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.