ReviewJournal of intensive care2017
Perfusion indices revisited.
Review in Journal of intensive care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 140 citations in OpenAlex.
- Meta-Analysis of the Prognostic Value of Skin Perfusion Parameters in Sepsis Patients: Evidence Integration Based on the Mottling Score, Capillary Refill Time, and Peripheral Perfusion Index.Shock (Augusta, Ga.) · 2026Pooled it
- [Association between peripheral perfusion, microcirculation and mortality in sepsis: a systematic review].Brazilian journal of anesthesiology (Elsevier)Pooled it
- Physiologic Determinants of Near-Infrared Spectroscopy-Derived Cerebral and Tissue Oxygen Saturation Measurements in Critically Ill Patients.Critical care explorations · 2024Trial
- Association between preoperative toe perfusion index and maternal core temperature decrease during cesarean delivery under spinal anesthesia: a prospective cohort study.BMC anesthesiology · 2021Trial
- Hemodynamic effects of norepinephrine versus phenylephrine infusion for prophylaxis against spinal anesthesia-induced hypotension in the elderly population undergoing hip fracture surgery: a randomized controlled trial.Korean journal of anesthesiology · 2021Trial
- Effects of nitroglycerin versus labetalol on peripheral perfusion during deliberate hypotension for sinus endoscopic surgery: a randomized, controlled, double-blinded trial.BMC anesthesiology · 2020Trial
- Peripheral perfusion noninvasive monitoring technologies - a literature and patent review.Journal of clinical monitoring and computing · 2026Review
- Analysis of heart rate variability in critical septic patients using a smartphone application: a prospective cohort study.Frontiers in medicine · 2026Article
- Role of Perfusion Index as a Predictor of Vasopressor Requirement in Patients With Sepsis.Cureus · 2025Article
- The Immediate Cardiovascular and Mitochondrial Response in Ischemic Cardiogenic Shock.Journal of cardiovascular translational research · 2025Article
- Review of Pulsation Signal Detection and Applications in Dynamic Photoacoustic Imaging.Biosensors · 2025Review
- Evaluation of intradialytic hypoxemia development in intensive care patients.BMC nephrology · 2025Observational
- Article
- Lactate infusion improves cardiac function in a porcine model of ischemic cardiogenic shock.Critical care (London, England) · 2025Article
- Correlation Between Activity Level of Renin-Angiotensin-Aldosterone System and Perfusion Index in Children with Postural Tachycardia Syndrome.Vascular health and risk management · 2025Article
- Accuracy of Perfusion Index and Perfusion Index Ratio as a Predictor of a Successful Low Interscalene Brachial Plexus Block: A Prospective Observational Study.Ochsner journal · 2025Article
- Construction and validation of a clinical prediction model for sepsis using peripheral perfusion index to predict in-hospital and 28-day mortality risk.Scientific reports · 2024Article
- Survival status and its predictors among adult victims of road traffic accident admitted to public hospitals of Bahir Bar City, Amhara regional state, Northwest, Ethiopia, 2023: multi center retrospective follow-up study.BMC emergency medicine · 2024Article
- Early peripheral perfusion monitoring in septic shock.European journal of medical research · 2024Review
- Peripheral perfusion index of pulse oximetry in adult patients: a narrative review.European journal of medical research · 2024Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Monitoring of tissue perfusion is an essential step in the management of acute circulatory failure. The presence of cellular dysfunction has been a basic component of shock definition even in the absence of hypotension. Monitoring of tissue perfusion includes biomarkers of global tissue perfusion and measures for assessment of perfusion in non-vital organs. The presence of poor tissue perfusion in a shocked patient is usually associated with worse outcome. Persistently impaired perfusion despite adequate resuscitation is also associated with worse outcome. Thus, normalization of some perfusion indices has become one of the resuscitation targets in patients with septic shock. Although the collective evidence shows the clear relation between impaired peripheral perfusion and mortality, the use of different perfusion indices as a resuscitation target needs more research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.