Evidence map›Paper›PMID 28331495›Full record

ArticleInternational journal of biomaterials2017

Development and In Vitro Evaluation of Liposomes Using Soy Lecithin to Encapsulate Paclitaxel.

Thi Lan Nguyen, Thi Hiep Nguyen, Dai Hai Nguyen

Open access · goldAbstract read
In one paragraph

Article in International journal of biomaterials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 71 citations in OpenAlex.

  1. Synthesis, Characterization, and Magnetic Properties of Fe(BIP)Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  2. Article
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  4. Fabrication of Phytosome with Enhanced Activity ofInternational journal of nanomedicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Thi Lan NguyenInstitute of Applied Materials Science, Vietnam Academy of Science and Technology, 01 TL29, District 12, Ho Chi Minh City, Vietnam; Can Tho University, 3/2 Street, Ninh Kieu District, Can Tho City, Vietnam.
Thi Hiep NguyenTissue Engineering and Regenerative Medicine Group, Department of Biomedical Engineering, International University, Vietnam National University-HCMC (VNU-HCMC), Ho Chi Minh City 70000, Vietnam.
Dai Hai NguyenInstitute of Applied Materials Science, Vietnam Academy of Science and Technology, 01 TL29, District 12, Ho Chi Minh City, Vietnam.ORCID 0000-0003-3501-7390
Vietnam National University Ho Chi Minh City · VNVietnam Academy of Science and Technology · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The formulation of a potential delivery system based on liposomes (Lips) formulated from soy lecithin (SL) for paclitaxel (PTX) was achieved (PTX-Lips). At first, PTX-Lips were prepared by thin film method using SL and cholesterol and then were characterized for their physiochemical properties (particle size, polydispersity index, zeta potential, and morphology). The results indicated that PTX-Lips were spherical in shape with a dynamic light scattering (DLS) particle size of 131 ± 30.5 nm. Besides, PTX was efficiently encapsulated in Lips, 94.5 ± 3.2% for drug loading efficiency, and slowly released up to 96 h, compared with free PTX. More importantly, cell proliferation kit I (MTT) assay data showed that Lips were biocompatible nanocarriers, and in addition the incorporation of PTX into Lips has been proven successful in reducing the toxicity of PTX. As a result, development of Lips using SL may offer a stable delivery system and promising properties for loading and sustained release of PTX in cancer therapy.

Identifiers

PMID28331495
PMCPMC5346369
OpenAlexW2589804382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.