Evidence map›Paper›PMID 28331318›Full record

ArticleInternational journal of nanomedicine2017

Surface-modified gatifloxacin nanoparticles with potential for treating central nervous system tuberculosis.

Patricia Marcianes, Sofia Negro, Luis García-García, Consuelo Montejo, Emilia Barcia, Ana Fernández-Carballido

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Article
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  8. Review
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  11. Article
  12. Impact of nanoparticles on neuron biology: current research trends.International journal of nanomedicine · 2018
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Patricia MarcianesDepartment of Pharmaceutics, School of Pharmacy, University Complutense of Madrid, Madrid, Spain.
Sofia NegroDepartment of Pharmaceutics, School of Pharmacy, University Complutense of Madrid, Madrid, Spain; Institute of Pharmaceutical Technology, University Complutense of Madrid, Madrid, Spain.
Luis García-GarcíaMultidisciplinary Institute of Cerebral Cartography, University Complutense of Madrid, Madrid, Spain.
Consuelo MontejoDepartment of Pharmaceutical and Health Sciences, School of Pharmacy, University CEU-San Pablo, Spain.
Emilia BarciaDepartment of Pharmaceutics, School of Pharmacy, University Complutense of Madrid, Madrid, Spain; Institute of Pharmaceutical Technology, University Complutense of Madrid, Madrid, Spain.
Ana Fernández-CarballidoDepartment of Pharmaceutics, School of Pharmacy, University Complutense of Madrid, Madrid, Spain; Institute of Pharmaceutical Technology, University Complutense of Madrid, Madrid, Spain.
Universidad Complutense de Madrid · ESUniversidad San Pablo CEU · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new nanocarrier is developed for the passage of gatifloxacin through the blood-brain barrier to treat central nervous system tuberculosis. Gatifloxacin nanoparticles were prepared by nanoprecipitation using poly(lactic-

Indexed as

AnimalsCerebral CortexChemistry, PharmaceuticalFluoroquinolonesGatifloxacinMaleMicroscopy, ConfocalNanoparticlesNeuronsRats, WistarRhodaminesSolutionsTissue DistributionTuberculosis, Central Nervous SystemFluoroquinolonesGatifloxacinRhodaminesSolutionsblood–brain barrierbrain deliverygatifloxacinLabrafilnanoparticlespolysorbate 80targeting

Identifiers

PMID28331318
PMCPMC5357078
OpenAlexW2597180564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.