Evidence map›Paper›PMID 28331316›Full record

ArticleInternational journal of nanomedicine2017

In vivo biodistribution and behavior of CdTe/ZnS quantum dots.

Yan Zhao, Yue Zhang, Gaofeng Qin, Jinjun Cheng, Wenhao Zeng, Shuchen Liu, Hui Kong, Xueqian Wang, Qingguo Wang, Huihua Qu

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Effect ofInternational journal of nanomedicine · 2020
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan ZhaoSchool of Basic Medical Sciences.
Yue ZhangSchool of Chinese Materia Medica.
Gaofeng QinSchool of Basic Medical Sciences.
Jinjun ChengSchool of Basic Medical Sciences.
Wenhao ZengSchool of Chinese Materia Medica.
Shuchen LiuSchool of Basic Medical Sciences.
Hui KongSchool of Basic Medical Sciences.
Xueqian WangSchool of Basic Medical Sciences.
Qingguo WangSchool of Basic Medical Sciences.
Huihua QuCenter of Scientific Experiment, Beijing University of Chinese Medicine, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The unique features of quantum dots (QDs) make them desirable fluorescent tags for cell and developmental biology applications that require long-term, multitarget, and highly sensitive imaging. In this work, we imaged fluorescent cadmium telluride/zinc sulfide (CdTe/ZnS) QDs in organs, tissues, and cells, and analyzed the mechanism of their lymphatic uptake and cellular distribution. We observed that the fluorescent CdTe/ZnS QDs were internalized by lymph nodes in four cell lines from different tissue sources. We obtained the fluorescence intensity-QD concentrations curve by quantitative analysis. Our results demonstrate that cells containing QDs can complete mitosis normally and that distribution of QDs was uniform across cell types and involved the vesicular transport system, including the endoplasmic reticulum. This capacity for CdTe/ZnS QD targeting provides insights into the applicability and limitations of fluorescent QDs for imaging biological specimens.

Indexed as

AnimalsCadmium CompoundsDiagnostic ImagingEndoplasmic ReticulumFemaleHuman Umbilical Vein Endothelial CellsIntracellular SpaceLymph NodesMiceMice, Inbred BALB CMicellesMitosisQuantum DotsRAW 264.7 CellsSpectrometry, FluorescenceSulfidesCadmium Compoundscadmium tellurideMicellesSulfidesTelluriumZinc Compoundszinc sulfidebiodistributionfluorescence imaginglymph nodesquantum dots

Identifiers

PMID28331316
PMCPMC5352250

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.