Evidence map›Paper›PMID 28331312›Full record

ArticleInternational journal of nanomedicine2017

Investigation of silk fibroin nanoparticle-decorated poly(l-lactic acid) composite scaffolds for osteoblast growth and differentiation.

Biao-Qi Chen, Ranjith Kumar Kankala, Ai-Zheng Chen, Ding-Zhu Yang, Xiao-Xia Cheng, Ni-Na Jiang, Kai Zhu, Shi-Bin Wang

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Article
  3. Enhanced Osteogenic Potential ofACS biomaterials science & engineering · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Biao-Qi ChenInstitute of Biomaterials and Tissue Engineering.
Ranjith Kumar KankalaInstitute of Biomaterials and Tissue Engineering; Fujian Provincial Key Laboratory of Biochemical Technology, Huaqiao University, Xiamen, Fujian.
Ai-Zheng ChenInstitute of Biomaterials and Tissue Engineering; Fujian Provincial Key Laboratory of Biochemical Technology, Huaqiao University, Xiamen, Fujian.
Ding-Zhu YangInstitute of Biomaterials and Tissue Engineering.
Xiao-Xia ChengInstitute of Biomaterials and Tissue Engineering.
Ni-Na JiangInstitute of Biomaterials and Tissue Engineering; Fujian Provincial Key Laboratory of Biochemical Technology, Huaqiao University, Xiamen, Fujian.
Kai ZhuDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University; Shanghai Institute of Cardiovascular Disease, Shanghai, People's Republic of China.
Shi-Bin WangInstitute of Biomaterials and Tissue Engineering; Fujian Provincial Key Laboratory of Biochemical Technology, Huaqiao University, Xiamen, Fujian.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attempts to reflect the physiology of organs is quite an intricacy during the tissue engineering process. An ideal scaffold and its surface topography can address and manipulate the cell behavior during the regeneration of targeted tissue, affecting the cell growth and differentiation significantly. Herein, silk fibroin (SF) nanoparticles were incorporated into poly(l-lactic acid) (PLLA) to prepare composite scaffolds via phase-inversion technique using supercritical carbon dioxide (SC-CO

Indexed as

Alkaline PhosphataseAnimalsCell AdhesionCell DifferentiationCell LineCell ProliferationCell SurvivalCollagenCollagen Type IFibroinsMiceNanoparticlesOsteoblastsOsteocalcinOsteogenesisPolyestersAlkaline PhosphataseCollagenCollagen Type IFibroinsOsteocalcinPolyesterspoly(lactide)alkaline phosphatasebone engineeringcellular adhesionsuper critical fluidssurface topography

Identifiers

PMID28331312
PMCPMC5352233

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.