Evidence map›Paper›PMID 28331232›Full record

ReviewNature reviews. Neuroscience2017

Motor compensation and its effects on neural reorganization after stroke.

Theresa A Jones

Registry-linked trialAbstract readReview
In one paragraph

Review in Nature reviews. Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06817512 (Health Effects of Vitamin K2 Supplementation on Skeletal Muscle and Neurological Function After Ischemic Stroke), which is not on this map. Cited by 190 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
190citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06817512 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Health Effects of Vitamin K2 Supplementation on Skeletal Muscle and Neurological Function After Ischemic Stroke

TypeinterventionalSponsorHarbin Medical UniversityRan2025 to 2028Enrolled190ConditionsIschemic StrokeArmsVitamin K2, Placebo
3 · Its place in the literature

Who cites it

190 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Guideline
  2. The Detrimental Effect of Stroke on Motor Adaptation.Neurorehabilitation and neural repair · 2025
    Pooled it
  3. Guideline
  4. Corticospinal Responses Following Gait-Specific Training in Stroke Survivors: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Kinect-based assessment of proximal arm non-use after a stroke.Journal of neuroengineering and rehabilitation · 2018
    Trial
  14. Trial
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

130 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Theresa A JonesDepartment of Psychology and Institute for Neuroscience, University of Texas at Austin, Texas 78712, USA.

Funding

Neural Mechanisms of Compensating for Brain DamageR01NS056839 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI JONES, THERESA A · 2007 to 2016
$3.3M
NEURAL MECHANISMS OF COMPENSATING FOR BRAIN DAMAGER37NS056839 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI JONES, THERESA A · 2018 to 2024
$2.6M
Neurovascular Mechanisms of Time-Dependencies in Stroke RehabilitationR01NS078791 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI DUNN, ANDREW K, JONES, THERESA A · 2012 to 2016
$1.7M
NINDS NIH HHS R01 NS056839NINDS NIH HHS R01 NS078791NINDS NIH HHS R37 NS056839
6 · The paper itself

Abstract

Stroke instigates a dynamic process of repair and remodelling of remaining neural circuits, and this process is shaped by behavioural experiences. The onset of motor disability simultaneously creates a powerful incentive to develop new, compensatory ways of performing daily activities. Compensatory movement strategies that are developed in response to motor impairments can be a dominant force in shaping post-stroke neural remodelling responses and can have mixed effects on functional outcome. The possibility of selectively harnessing the effects of compensatory behaviour on neural reorganization is still an insufficiently explored route for optimizing functional outcome after stroke.

Indexed as

Stroke RehabilitationAdaptation, PhysiologicalHumansNerve RegenerationNeuronal PlasticityRecovery of FunctionStroke

Identifiers

PMID28331232
PMCPMC6289262

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.