ArticleScientific reports2017
Unraveling the mystery of hearing in gerbil and other rodents with an arch-beam model of the basilar membrane.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- How the Human Cochlea Moves: Biomechanical Modeling of a Wide, Layered Osseous Spiral Lamina.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- Visualizing Collagen Fibrils in the Cochlea's Tectorial and Basilar Membranes Using a Fluorescently Labeled Collagen-Binding Protein Fragment.Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- Cochlear motion across the reticular lamina implies that it is not a stiff plate.Scientific reports · 2022Article
- Cochlear Fluid Spaces and Structures of the Gerbil High-Frequency Region Measured Using Optical Coherence Tomography (OCT).Journal of the Association for Research in Otolaryngology : JARO · 2022Article
- Using volumetric optical coherence tomography to achieve spatially resolved organ of Corti vibration measurements.The Journal of the Acoustical Society of America · 2022Article
- Nonlinearity of intracochlear motion and local cochlear microphonic: Comparison between guinea pig and gerbil.Hearing research · 2021Article
- Pup ultrasonic isolation calls of six gerbil species and the relationship between acoustic traits and body size.Royal Society open science · 2021Article
- Emilin 2 promotes the mechanical gradient of the cochlear basilar membrane and resolution of frequencies in sound.Science advances · 2020Article
- Cochlear partition anatomy and motion in humans differ from the classic view of mammals.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Cochlear amplification and tuning depend on the cellular arrangement within the organ of Corti.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Hydrostatic measurement and finite element simulation of the compliance of the organ of Corti complex.The Journal of the Acoustical Society of America · 2018Article
- Nonlinear cochlear mechanics without direct vibration-amplification feedback.Physical review researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
The mammalian basilar membrane (BM) consists of two collagen-fiber layers responsible for the frequency-to-place tonotopic mapping in the cochlea, which together form a flat beam over at least part of the BM width. The mechanics of hearing in rodents such as gerbil pose a challenge to our understanding of the cochlea, however, because for gerbil the two layers separate to form a pronounced arch over the remaining BM width. Moreover, the thickness and total width normally thought to determine the local stiffness, and tonotopic mapping in turn, change little along the cochlear length. A nonlinear analysis of a newly developed model, incorporating flat upper and arched lower fiber layers connected by ground substance, explains the initial plateau and subsequent quadratic increase found in measured stiffness vs. deflection curves under point loading, while for pressure loading the model accurately predicts the tonotopic mapping. The model also has applicability to understanding cochlear development and to interpreting evolutionary changes in mammalian hearing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.