ArticleJournal of virology2017
Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages.
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Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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0cells of the map it votes in
57citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 78 citations in OpenAlex.
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- Temporal transcriptomics identifies early-response and infection-condition-specific modules guiding host-directed anti-EBOV therapeutics.Microbiology spectrum · 2026Article
- Review
- Ebola virus matrix protein VP40 triggers inflammatory responses linked to the ebolavirus virulence.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Filovirus infection disrupts epithelial barrier function and ion transport in human iPSC-derived gut organoids.PLoS pathogens · 2025Article
- A protein-proximity screen reveals Ebola virus co-opts the mRNA decapping complex through the scaffold protein EDC4.Nature communications · 2025Article
- Early events in dengue virus infection inducing cytokine storm: The dynamic interplay of pattern-recognition receptors, inflammasome activation, and biphasic NF-κB and STAT1-dependent inflammatory responses in human mononuclear phagocytes.PLoS neglected tropical diseases · 2025Article
- Harnessing Hazara Virus as a Surrogate for Crimean-Congo Hemorrhagic Fever Virus Enables Inactivation Studies at a Low Biosafety Level.Pathogens (Basel, Switzerland) · 2025Article
- Immunoinformatic-driven design and evaluation of multi-epitope mRNA vaccine targeting HIV-1 gp120.Frontiers in immunology · 2025Article
- Marburg and Sudan viruses elicit divergent interferon responses and cytokine storm signaling in Egyptian rousette bat macrophages.Frontiers in immunology · 2025Article
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- Immunoinformatics and Reverse Vaccinology Approach for the Identification of Potential Vaccine Candidates againstMicroorganisms · 2024Article
- Human macrophages infected with Egyptian Rousette bat-isolated Marburg virus display inter-individual susceptibility and antiviral responsiveness.Npj viruses · 2024Article
- Sodium Butyrate Induced Neural Stem/Progenitor Cell Death in an Experimental Model of Japanese Encephalitis.Metabolic brain disease · 2023Article
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- Art of the Kill: Designing and Testing Viral Inactivation Procedures for Highly Pathogenic Negative Sense RNA Viruses.Pathogens (Basel, Switzerland) · 2023Article
- Extracellular vesicle storm during the course of Ebola virus infection in primates.Frontiers in cellular and infection microbiology · 2023Article
- Filoviruses: Innate Immunity, Inflammatory Cell Death, and Cytokines.Pathogens (Basel, Switzerland) · 2022Review
- Labeling Ebola Virus with a Self-Splicing Fluorescent Reporter.Microorganisms · 2022Article
- Activation of Toll-like receptor 4 by Ebola virus-shed glycoprotein is direct and requires the internal fusion loop but not glycosylation.Cell reports · 2022Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Judith OlejnikDepartment of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA.
Adriana ForeroDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
Laure R DeflubéDepartment of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA.
Adam J HumeDepartment of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA.
Whitney A ManhartDepartment of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA.
Andrew NishidaDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
Andrea MarziLaboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana, USA.
Michael G KatzeDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
Hideki EbiharaLaboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana, USA.
Angela L RasmussenDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
Elke MühlbergerDepartment of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA muehlber@bu.edu.
Boston University · USUniversity of Washington · USNational Institute of Allergy and Infectious Diseases · USNational Institutes of Health · US
Funding
National Center/Emerging Infectous Diseases &BiodefenseUC6AI058618 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MURPHY, JOHN R. · 2003 to 2006
$141.0MViral Hemorrhagic Fevers: Disease Modeling and TransmissionZIAAI001089 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI FELDMANN, HEINRICH · 2009 to 2025
$50.7MTranslational CoreU19AI109761 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BARIC, RALPH S · 2014 to 2018
$32.6MEarly Host Immune Response in Protection Against Filovirus InfectionU01AI082954 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MUHLBERGER, ELKE C · 2009 to 2013
$3.3MFilovirus replication: initiation mechanism and role of RNA secondary structuresR03AI114293 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MUHLBERGER, ELKE C · 2014 to 2015
$164kNIAID NIH HHS R03 AI114293NIAID NIH HHS U01 AI082954NIAID NIH HHS U19 AI109761NIAID NIH HHS UC6 AI058618
Abstract
Ebola virus (EBOV) and Reston virus (RESTV) are members of the
Indexed as
Host-Pathogen InteractionsAnimalsCell LineChemokinesChlorocebus aethiopsCytokinesDendritic CellsEbolavirusGene Expression ProfilingHumansInterferon Regulatory Factor-3InterferonsMacrophagesNF-kappa B p50 SubunitToll-Like Receptor 4Vero CellsChemokinesCytokinesInterferon Regulatory Factor-3InterferonsIRF3 protein, humanNF-kappa B p50 SubunitNFKB1 protein, humanTLR4 protein, humanToll-Like Receptor 4chemokinescytokinesEbola virusfilovirushost responseinterferonsmacrophagesReston virusToll-like receptor 4Toll-like receptors
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.