Evidence map›Paper›PMID 28330968›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2017

Examination of carnitine palmitoyltransferase 1 abundance in white adipose tissue: implications in obesity research.

Jaycob D Warfel, Bolormaa Vandanmagsar, Olga S Dubuisson, Sydney M Hodgeson, Carrie M Elks, Eric Ravussin, Randall L Mynatt

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 62 citations in OpenAlex.

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  16. E4orf1 Prevents Progression of Fatty Liver Disease in Mice on High Fat Diet.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jaycob D WarfelGene Nutrient Interactions Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana.
Bolormaa VandanmagsarGene Nutrient Interactions Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana.
Olga S DubuissonGene Nutrient Interactions Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana.
Sydney M HodgesonGene Nutrient Interactions Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana.
Carrie M ElksMatrix Biology Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana; and.
Eric RavussinJohn S. McIlhenny Skeletal Muscle Physiology Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana.
Randall L MynattGene Nutrient Interactions Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana; mynattrl@pbrc.edu.
Louisiana State University · USPennington Biomedical Research Center · US

Funding

Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Leanne Maree Redman · 2005 to 2026
$26.5M
Mentoring Obesity and Diabetes Research in LouisianaP20GM103528 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI GETTYS, THOMAS W · 2012 to 2015
$8.8M
Training in Obesity ResearchT32DK064584 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI CORBY K MARTIN, Christopher D Morrison · 2003 to 2026
$5.3M
Molecular Genetics of ThermogenesisR01DK089641 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI MYNATT, RANDALL LEE, YOUNG, MARTIN E · 2010 to 2013
$1.6M
Inhibition of CPT-1b in muscle: effects on glucose homeostasisR01DK098687 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI MYNATT, RANDALL LEE · 2013 to 2017
$1.6M
The Effects of Oncostatin M on the Adipose Tissue Extracellular MatrixK01DK106307 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI ELKS, CARRIE M · 2016 to 2019
$508k
NIDDK NIH HHS K01 DK106307NIDDK NIH HHS P30 DK072476NIDDK NIH HHS R01 DK089641NIDDK NIH HHS R01 DK098687NIDDK NIH HHS T32 DK064584NIGMS NIH HHS P20 GM103528
6 · The paper itself

Abstract

Carnitine palmitoyltransferase 1 (CPT1) is essential for the transport of long-chain fatty acids into the mitochondria for oxidation. Recently, it was reported that decreased CPT1b mRNA in adipose tissue was a contributing factor for obesity in rats. We therefore closely examined the expression level of

Indexed as

Gene Expression Regulation, EnzymologicAdipose Tissue, WhiteAdultAgedAnimalsCarnitine O-PalmitoyltransferaseEnzyme ActivationFemaleHumansMaleMiceMice, Inbred C57BLMiddle AgedObesityOrgan SpecificityRatsCarnitine O-Palmitoyltransferaseadipose tissueCpt1aCpt1blipid oxidation, obesity

Identifiers

PMID28330968
PMCPMC5451572
OpenAlexW2603850085

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.