Evidence map›Paper›PMID 28330875›Full record

ArticleThe Journal of biological chemistry2017

Lysine 300 is essential for stability but not for electrogenic transport of the

Octavian Călinescu, Manish Dwivedi, Miyer Patiño-Ruiz, Etana Padan, Klaus Fendler

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. pH-dependent activation of the NaNature communications · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Prokaryotic NaInternational journal of molecular sciences · 2022
    Review
  6. The Remaining Conundrum of the Role of the NaReviews in cardiovascular medicine · 2022
    Review
  7. Review
  8. Alternative proton-binding site and long-distance coupling inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  9. Article
  10. Review
  11. Article
  12. Replacement of Lys-300 with a glutamine in the NhaA NaThe Journal of biological chemistry · 2019
    Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Octavian CălinescuFrom the Max-Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany.
Manish Dwivedithe Institute of Life Sciences, Hebrew University of Jerusalem, 91904 Jerusalem, Israel.
Miyer Patiño-RuizFrom the Max-Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany.
Etana Padanthe Institute of Life Sciences, Hebrew University of Jerusalem, 91904 Jerusalem, Israel.
Klaus FendlerFrom the Max-Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany, fendler@biophys.mpg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Na

Indexed as

Biological TransportBiological Transport, ActiveCrystallography, X-RayEscherichia coliEscherichia coli ProteinsFluorometryHydrogen-Ion ConcentrationLysineMutagenesis, Site-DirectedMutationPhenotypeProtein Structure, SecondaryProtein TransportSodium-Hydrogen ExchangersSpectrometry, FluorescenceEscherichia coli ProteinsLysineNhaA protein, E coliSodium-Hydrogen Exchangerselectrophysiologyenzyme mechanismmembrane transportsecondary active transportsite-directed mutagenesissodium-proton exchangetransportertransport mechanism

Identifiers

PMID28330875
PMCPMC5427271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.