ArticleScience translational medicine2017
Bacterial virulence phenotypes of
Abstract read
In one paragraph
Article in Science translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
102 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Recurrent urinary tract infection genetic risk: a systematic review and gene network analysis.International urogynecology journal · 2024Pooled it
- Trial
- Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections.BMC microbiology · 2021Trial
- In vivo CRISPRi screens reveal Escherichia coli functional adaptations in the mouse gut.Nature microbiology · 2026Article
- Cytolethal distending toxin enhancesInfection and immunity · 2026Article
- Function-specific epistasis shapes evolutionary trajectories towards antibiotic resistance.Nature communications · 2026Article
- Significant variability in virulence factors and antibiotic resistance of uropathogenic Escherichia coli strains may be counteracted by their susceptibility to lytic bacteriophages.Scientific reports · 2026Article
- Article
- Implications for methenamine hippurate use in recurrent urinary tract infection management: Formaldehyde resistance and altered urinary composition.PLoS pathogens · 2026Article
- Cytolethal Distending Toxin EnhancesbioRxiv : the preprint server for biology · 2026Article
- Whole-genome characterisation of Escherichia coli isolates from older women with urinary tract infection and asymptomatic bacteriuria.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- The Yeh pilus adhesin is equipped with an α-helical flap motif, which contributes to pectin adherence.Science advances · 2026Article
- Loss of Type 1 Pili and Flagella in UropathogenicPathogens (Basel, Switzerland) · 2025Article
- Stem cell-derived exosomes in complicated urinary tract infections: immunomodulatory mechanisms and potential therapeutic strategies for urothelial repair.Stem cell research & therapy · 2025Review
- Efficacy and Safety of Uro-Vaxom in Urinary Tract Infection Prevention: A Systematic Literature Review.Journal of clinical medicine · 2025Review
- Article
- Rapid and accurate testing for urinary tract infection: new clothes for the emperor.Clinical microbiology reviews · 2025Review
- Ameba-inspired strategy enhances probiotic efficacy via prebound nutrient supply.Nature communications · 2025Article
- Urinary tract infections: pathogenesis, host susceptibility and emerging therapeutics.Nature reviews. Microbiology · 2025Review
- Mechanisms of uropathogenicScience advances · 2025Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
13 authors.
Henry L SchreiberDepartment of Molecular Microbiology, Washington University, St. Louis, MO 63110, USA.ORCID 0000-0002-4501-9886
Matt S ConoverDepartment of Molecular Microbiology, Washington University, St. Louis, MO 63110, USA.ORCID 0000-0001-6834-6831
Wen-Chi ChouBroad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA.ORCID 0000-0001-8408-3533
Michael E HibbingDepartment of Molecular Microbiology, Washington University, St. Louis, MO 63110, USA.ORCID 0000-0002-0072-6210
Abigail L MansonBroad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA.ORCID 0000-0002-3800-0714
Karen W DodsonDepartment of Molecular Microbiology, Washington University, St. Louis, MO 63110, USA.
Thomas J HannanDepartment of Pathology and Immunology, Washington University, St. Louis, MO 63110, USA.ORCID 0000-0003-0498-8231
Pacita L RobertsDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98195, USA.
Ann E StapletonDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0003-0130-8659
Thomas M HootonDivision of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0001-5810-6543
Jonathan LivnyBroad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA. livny@broadinstitute.org aearl@broadinstitute.org hultgren@wusm.wustl.edu.ORCID 0000-0001-6589-3020
Ashlee M EarlBroad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA. livny@broadinstitute.org aearl@broadinstitute.org hultgren@wusm.wustl.edu.ORCID 0000-0001-7857-9145
Scott J HultgrenDepartment of Molecular Microbiology, Washington University, St. Louis, MO 63110, USA. livny@broadinstitute.org aearl@broadinstitute.org hultgren@wusm.wustl.edu.ORCID 0000-0001-8785-564X
Funding
Viral Genomics: evolution, spread, and host interactionsU19AI110818 · NIAID · BROAD INSTITUTE, INC. · PI EARL, ASHLEE MIRIAM · 2014 to 2024
$66.5Mpan-Genome of E.coli in the bladder and gut of women with recurrent UTIP50DK064540 · NIDDK · WASHINGTON UNIVERSITY · PI HULTGREN, SCOTT J. · 2002 to 2017
$17.9MMucosal Immune Defense Mechanisms of the Urinary BladderU01AI095542 · NIAID · WASHINGTON UNIVERSITY · PI COLONNA, MARCO, HULTGREN, SCOTT J. · 2011 to 2020
$9.8MMOLECULAR BASIS OF E. COLI ADHESINS IN BLADDER DISORDERSR01DK051406 · NIDDK · WASHINGTON UNIVERSITY · PI SCOTT J. HULTGREN · 1997 to 2026
$8.8MLactobacillus probiotic for prevention of recurrent UTIR01DK088830 · NIDDK · UNIVERSITY OF WASHINGTON · PI STAPLETON, ANN E · 2011 to 2015
$3.0MMucosal Immune Checkpoints in Chronic Bacterial CystitisK08AI083746 · NIAID · WASHINGTON UNIVERSITY · PI HANNAN, THOMAS JOSEPH · 2009 to 2011
$356kNIAID NIH HHS K08 AI083746NIAID NIH HHS U01 AI095542NIAID NIH HHS U19 AI110818NIDDK NIH HHS P50 DK064540NIDDK NIH HHS R01 DK051406NIDDK NIH HHS R01 DK088830
Abstract
Urinary tract infections (UTIs) are caused by uropathogenic
Indexed as
Disease SusceptibilityHost-Pathogen InteractionsAnimalsBiomarkersChronic DiseaseCoinfectionColony Count, MicrobialCystitisEscherichia coliEscherichia coli InfectionsFemaleGene Expression Regulation, BacterialHumansMiceMice, Inbred StrainsPhenotypeBiomarkersVirulence Factors
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.