Observational studyJournal of the American Medical Directors Association2017
The Association Between Muscle Weakness and Incident Diabetes in Older Mexican Americans.
Observational study in Journal of the American Medical Directors Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Clinical importance of simple muscular fitness tests to predict long-term health conditions: a systematic review and meta-analysis of 94 cohort studies.British journal of sports medicine · 2026Pooled it
- Association between muscle strength and cardiometabolic multimorbidity risk among middle-aged and older Chinese adults: a nationwide longitudinal cohort study.BMC public health · 2024Article
- Associations of Abdominal Muscle Density and Area and Incident Cardiovascular Disease, Coronary Heart Disease, and Stroke: The Multi-Ethnic Study of Atherosclerosis.Journal of the American Heart Association · 2024Article
- Hand grip strength as a proposed new vital sign of health: a narrative review of evidences.Journal of health, population, and nutrition · 2024Review
- Prediabetes-Associated Changes in Skeletal Muscle Function and Their Possible Links with Diabetes: A Literature Review.International journal of molecular sciences · 2023Review
- Gender-Specific Association of Handgrip Strength with Type 2 Diabetes Mellitus in Chinese Han Older Adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Association between handgrip strength and the risk of new-onset metabolic syndrome: a population-based cohort study.BMJ open · 2020Article
- Muscle area and density and risk of all-cause mortality: The Multi-Ethnic Study of Atherosclerosis.Metabolism: clinical and experimental · 2020Article
- Glucose Levels as a Mediator of the Detrimental Effect of Abdominal Obesity on Relative Handgrip Strength in Older Adults.Journal of clinical medicine · 2020Article
- Muscle strength cut-offs for the detection of metabolic syndrome in a nonrepresentative sample of collegiate students from Colombia.Journal of sport and health science · 2020Article
- Relative Handgrip Strength Diminishes the Negative Effects of Excess Adiposity on Dependence in Older Adults: A Moderation Analysis.Journal of clinical medicine · 2020Article
- Article
- Nativity, Neighborhoods, and Body Composition in the Sacramento Area Latino Study on Aging.The Gerontologist · 2020Article
- What are the association patterns between handgrip strength and adverse health conditions? A topical review.SAGE open medicine · 2020Review
- A Narrative Review of Handgrip Strength and Cognitive Functioning: Bringing a New Characteristic to Muscle Memory.Journal of Alzheimer's disease : JAD · 2020Review
- Handgrip Strength and Health in Aging Adults.Sports medicine (Auckland, N.Z.) · 2018Article
- The Association Between Handgrip Strength and Diabetes on Activities of Daily Living Disability in Older Mexican Americans.Journal of aging and health · 2018Article
- Observational
- Muscle Strength and Functional Limitations: Preserving Function in Older Mexican Americans.Journal of the American Medical Directors Association · 2018Article
- Low Handgrip Strength Is Not Associated with Type 2 Diabetes Mellitus and Hyperglycemia: a Population-Based Study.Clinical nutrition research · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesA natural decline of muscle strength occurs during the aging process; however, preserving muscle strength may lower the rate of many preventable diseases such as diabetes, especially in higher risk populations. The purpose of this study was to examine the sex-specific association between muscle weakness and incident diabetes in older Mexican Americans.
designObservational, longitudinal study.
settingUrban and rural households in the Southwestern United States.
participantsA subsample of 1903 Mexican Americans aged at least 65 years without diabetes at baseline were followed for 19 years. MEASUREMENTS: Muscle weakness was assessed with a hand-held dynamometer and was normalized to body weight (normalized grip strength). Male and female participants were categorized as weak if their normalized grip strength was ≤0.46 and ≤0.30, respectively. Sex-stratified Cox proportional hazard regression models were used to determine the association between muscle weakness and incident diabetes (self-reported) when using age as an entry variable and after adjusting for education, employment status, instrumental activities of daily living disability, interview language, marital status, and obesity. A sensitivity analysis was performed to account for influential outliers for the outcome variable (incident diabetes) and the model was re-run.
resultsThe hazard ratio for incident diabetes was 1.05 (95% confidence interval: 1.02-1.09; P < .001) in weak vs not-weak male participants and 1.38 (95% confidence interval: 1.35-1.41; P < .001) in weak vs not-weak female participants, after adjusting for relevant covariates.
conclusionsMuscle weakness was associated with an increased rate of diabetes in older male and female Mexican Americans. Health professionals should encourage activities that preserve muscle strength, thereby preventing the incidence of diabetes in older Mexican Americans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.