ArticleBMC endocrine disorders2017
Impaired lung function is associated with non-alcoholic fatty liver disease independently of metabolic syndrome features in middle-aged and elderly Chinese.
Article in BMC endocrine disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Chronic obstructive pulmonary disease and risk of digestive diseases: observational and mendelian randomization analyses in the China Kadoorie Biobank.Respiratory research · 2026Observational
- Review
- Lung function and nonalcoholic fatty liver disease: a Mendelian randomization study.Archives of medical science : AMS · 2025Article
- Association between metabolic dysfunction-associated steatotic liver disease and pulmonary function: a population-based and two-sample mendelian randomization study.BMC pulmonary medicine · 2024Article
- Combined Exercise and Diet Induce Airway Hyperreactivity While Reducing Liver Steatosis in Mice with Diet-Induced Obesity.Nutrients · 2024Article
- Metabolic Dysfunction-associated Fatty Liver Disease is Associated with Greater Impairment of Lung Function than Nonalcoholic Fatty Liver Disease.Journal of clinical and translational hepatology · 2022Article
- Increased Oxygen Desaturation Time During Sleep Is a Risk Factor for NASH in Patients With Obstructive Sleep Apnea: A Prospective Cohort Study.Frontiers in medicine · 2022Article
- Pulmonary function test abnormalities in children and adolescents with non-alcoholic fatty liver disease.European journal of pediatrics · 2021Article
- Visceral adiposity index is associated with lung function impairment: a population-based study.Respiratory research · 2021Article
- Sarcopenia Is an Independent Risk Factor for NAFLD in COPD: A Nationwide Survey (KNHANES 2008-2011).International journal of chronic obstructive pulmonary disease · 2020Article
- Association between dietary iron intake and the prevalence of nonalcoholic fatty liver disease: A cross-sectional study.Medicine · 2019Article
- Decreased lung function is associated with risk of developing non-alcoholic fatty liver disease: A longitudinal cohort study.PloS one · 2019Article
- Risk factors and community intervention for nonalcoholic fatty liver disease in community residents of Urumqi, China.Medicine · 2018Observational
- Relationship between obstructive lung disease and non-alcoholic fatty liver disease in the Korean population: Korea National Health and Nutrition Examination Survey, 2007-2010.International journal of chronic obstructive pulmonary disease · 2018Article
- Non-specific impairment of Lung Function on Spirometery in Patients with Chronic Hepatitis-C.Pakistan journal of medical sciencesArticle
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAssociations between lung function and non-alcoholic fatty liver disease (NAFLD) have been reported. However, evidence from large-scale populations about the relationship is scarce. The objective of the study was to evaluate the relationship between lung function and NAFLD in middle-aged and elderly Chinese.
methodsA total of 1842 participants aged 40 years or older were recruited from Chongming District, Shanghai, China. Lung function, evaluated by forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) was measured with standard spirometry. The NAFLD was evaluated by ultrasonography.
resultsThe subjects with NAFLD had lower FVC (% predicted) (0.85 ± 0.26 vs. 0.90 ± 0.28, p < 0.001) and FEV1 (% predicted) (0.93 ± 0.29 vs. 0.98 ± 0.34, p < 0.001) than non-NAFLD. After adjusting for potential risk factors, the lowest quartile of FVC (% predicted) and FEV1 (% predicted) was associated with increased prevalence of NAFLD, with the fully adjusted odds ratio of 1.37 and 1.24 (95% confidence interval [CI] 1.18-1.97, p < 0.001, 95% CI 1.11-1.87, p = 0.009), respectively.
conclusionsImpaired lung function is associated with non-alcoholic fatty liver disease, independent of conventional metabolic risk factors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.