Article3 Biotech2016
Antioxidant and antiplatelet activities of flavonoid-rich fractions of three citrus fruits from Korea.
Article in 3 Biotech, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 52 citations in OpenAlex.
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- Crosstalk Between Antioxidants and Adipogenesis: Mechanistic Pathways and Their Roles in Metabolic Health.Antioxidants (Basel, Switzerland) · 2025Review
- Evaluation of the physical, antioxidant, and organoleptic properties of biscuits fortified with edible flower powders.Food science & nutrition · 2024Article
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- Bioactive Components and Anticancer Activities of Spray-Dried New Zealand Tamarillo Powder.Molecules (Basel, Switzerland) · 2022Article
- Detection of Volatiles by HS-SPME-GC/MS and Biological Effect Evaluation of Buddha's Hand Fruit.Molecules (Basel, Switzerland) · 2022Article
- An evaluation of the phytochemical composition, antioxidant and cytotoxicity of the leaves ofSaudi journal of biological sciences · 2022Article
- UPLC-PDA-ESI-QTOF-MS/MS fingerprint of purified flavonoid enriched fraction ofPharmaceutical biology · 2021Article
- A Comparative Study of the Chemical Composition by SPME-GC/MS and Antiradical Activity of Less CommonMolecules (Basel, Switzerland) · 2021Article
- CUPRAC-Reactive Advanced Glycation End Products as Prognostic Markers of Human Acute Myocardial Infarction.Antioxidants (Basel, Switzerland) · 2021Article
- Yuzu and Hesperidin Ameliorate Blood-Brain Barrier Disruption during Hypoxia via Antioxidant Activity.Antioxidants (Basel, Switzerland) · 2020Article
- Beneficial Effects of Citrus Flavonoids on Cardiovascular and Metabolic Health.Oxidative medicine and cellular longevity · 2019Review
- Phenolic Compositions and Antioxidant Activities Differ Significantly among Sorghum Grains with Different Applications.Molecules (Basel, Switzerland) · 2018Article
- Effect of Polyphenols FromFrontiers in pharmacology · 2018Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Three different fractional (methanol, ethyl acetate and hexane) extracts from yuzu (Citrus junos Sieb ex Tanaka), hallabong [(C. unshiu Marcov × C. sinensis Osbeck) × C. reticulata Blanco] and orange (C. sinensis) were evaluated for their antioxidant activity and antiplatelet effects. 2,2-Diphenyl-1-Picrylhydrazyl (DPPH), cupric reducing antioxidant capacity (CUPRAC) and ferric-reducing antioxidant power (FRAP) methods were used for the antioxidant activity tests. Total flavonoids and total phenolics were also evaluated spectrophotometrically. The ethyl acetate fraction contained the highest total flavonoid and total phenolic content and exhibited the highest antioxidant activities (185.2 ± 14.5 and 208.7 ± 17.5 mg/g dry extract for FRAP and CUPRAC values, respectively). The total phenolic and total flavonoid content ranged from 58.2 ± 1.4 to 102.4 ± 8.6 and 19.6 ± 0.5 to 64.3 ± 0.8 mg/g dry extract, respectively. The results of DPPH assay showed that ethyl acetate fractions had the least IC50 values (0.12 ± 0.002, 0.04 ± 0.0006, in mg/mL for orange and hallabong samples, respectively) followed by the hexane fraction (0.19 ± 0.007 mg/mL) of the orange sample. For all fractions, the antioxidant activity and contents of total phenolics and total flavonoids correlated well with each other. In vitro investigation of the antiplatelet effect showed that ethyl acetate fraction has the highest inhibition (84.3 ± 5.8 to 96.1 ± 1.8 %). Hexane and MeOH fractions of hallabong and orange samples inhibited platelet aggregations by less than or equal to 41 %.
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